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Combination therapy with anti-CTLA-4 and anti-PD-1 leads to distinct immunologic changes in vivo.
Das, Rituparna; Verma, Rakesh; Sznol, Mario; Boddupalli, Chandra Sekhar; Gettinger, Scott N; Kluger, Harriet; Callahan, Margaret; Wolchok, Jedd D; Halaban, Ruth; Dhodapkar, Madhav V; Dhodapkar, Kavita M.
Affiliation
  • Das R; Department of Medicine, Yale University School of Medicine, New Haven, CT 06520; Smilow Cancer Center, Yale University School of Medicine, New Haven, CT 06520;
  • Verma R; Department of Medicine, Yale University School of Medicine, New Haven, CT 06520; Smilow Cancer Center, Yale University School of Medicine, New Haven, CT 06520;
  • Sznol M; Department of Medicine, Yale University School of Medicine, New Haven, CT 06520; Smilow Cancer Center, Yale University School of Medicine, New Haven, CT 06520;
  • Boddupalli CS; Department of Medicine, Yale University School of Medicine, New Haven, CT 06520; Smilow Cancer Center, Yale University School of Medicine, New Haven, CT 06520;
  • Gettinger SN; Department of Medicine, Yale University School of Medicine, New Haven, CT 06520; Smilow Cancer Center, Yale University School of Medicine, New Haven, CT 06520;
  • Kluger H; Department of Medicine, Yale University School of Medicine, New Haven, CT 06520; Smilow Cancer Center, Yale University School of Medicine, New Haven, CT 06520;
  • Callahan M; Ludwig Center for Cancer Immunotherapy, Memorial Sloan-Kettering Cancer Center, New York, NY 10065;
  • Wolchok JD; Ludwig Center for Cancer Immunotherapy, Memorial Sloan-Kettering Cancer Center, New York, NY 10065;
  • Halaban R; Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520; and.
  • Dhodapkar MV; Department of Medicine, Yale University School of Medicine, New Haven, CT 06520; Smilow Cancer Center, Yale University School of Medicine, New Haven, CT 06520;
  • Dhodapkar KM; Department of Medicine, Yale University School of Medicine, New Haven, CT 06520; Smilow Cancer Center, Yale University School of Medicine, New Haven, CT 06520; Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 kavita.dhodapkar@yale.edu.
J Immunol ; 194(3): 950-9, 2015 Feb 01.
Article in En | MEDLINE | ID: mdl-25539810
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CTLA-4 Antigen / Programmed Cell Death 1 Receptor / Neoplasms Limits: Humans Language: En Journal: J Immunol Year: 2015 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CTLA-4 Antigen / Programmed Cell Death 1 Receptor / Neoplasms Limits: Humans Language: En Journal: J Immunol Year: 2015 Type: Article