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Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis.
Napolitano, Gennaro; Johnson, Jennifer L; He, Jing; Rocca, Celine J; Monfregola, Jlenia; Pestonjamasp, Kersi; Cherqui, Stephanie; Catz, Sergio D.
Affiliation
  • Napolitano G; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA.
  • Johnson JL; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA.
  • He J; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA.
  • Rocca CJ; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.
  • Monfregola J; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA.
  • Pestonjamasp K; Cancer Center Microscopy Shared Resource, University of California San Diego, La Jolla, CA, USA.
  • Cherqui S; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.
  • Catz SD; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA scatz@scripps.edu.
EMBO Mol Med ; 7(2): 158-74, 2015 Feb.
Article in En | MEDLINE | ID: mdl-25586965
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Molecular Chaperones / Cystinosis / Amino Acid Transport Systems, Neutral / Lysosomal-Associated Membrane Protein 2 / Lysosomes Limits: Animals / Humans Language: En Journal: EMBO Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2015 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Molecular Chaperones / Cystinosis / Amino Acid Transport Systems, Neutral / Lysosomal-Associated Membrane Protein 2 / Lysosomes Limits: Animals / Humans Language: En Journal: EMBO Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2015 Type: Article Affiliation country: United States