Identification of secretaglobin Scgb2a1 as a target for developmental reprogramming by BPA in the rat prostate.

Wong, Rebecca Lee Yean; Wang, Quan; Treviño, Lindsey S; Bosland, Maarten C; Chen, Jing; Medvedovic, Mario; Prins, Gail S; Kannan, Kurunthachalam; Ho, Shuk-Mei; Walker, Cheryl Lyn

Wong, Rebecca Lee Yean; Wang, Quan; Treviño, Lindsey S; Bosland, Maarten C; Chen, Jing; Medvedovic, Mario; Prins, Gail S; Kannan, Kurunthachalam; Ho, Shuk-Mei; Walker, Cheryl Lyn.

Affiliation

Wong RL; a Center for Translational Cancer Research; Institute of Biosciences and Technology ; The Texas A&M University System Health Science Center ; Houston , TX USA.

Epigenetics ; 10(2): 127-34, 2015.

Article in En | MEDLINE | ID: mdl-25612011

Subject(s)

Benzhydryl Compounds/toxicity; Cellular Reprogramming/drug effects; Estrogens, Non-Steroidal/toxicity; Mammaglobin B/metabolism; Phenols/toxicity; Prostate/drug effects; Prostate/metabolism; Acetylation; Animals; Animals, Newborn; CpG Islands/drug effects; DNA Methylation/drug effects; Histones/metabolism; Lysine/metabolism; Male; Promoter Regions, Genetic/drug effects; Prostate/growth & development; Prostatic Hyperplasia/chemically induced; Rats, Sprague-Dawley; Up-Regulation/drug effects

Key words

BPA; BPA, Bisphenol A; ChIP, chromatin immunoprecipitation; DNA methylation; E, Estrogen; EDCs, Endocrine Disrupting Compounds; PIN, Prostatic Intraepithelial Neoplasia; RNA-seq, RNA-sequencing.; Scgb2a1; T, Testosterone; developmental reprogramming; prostate cancer; prostatein; qRT-PCR, quantitative real-time PCR

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenols / Prostate / Benzhydryl Compounds / Estrogens, Non-Steroidal / Cellular Reprogramming / Mammaglobin B Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Epigenetics Journal subject: GENETICA Year: 2015 Type: Article

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