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CH5137291, an androgen receptor nuclear translocation-inhibiting compound, inhibits the growth of castration-resistant prostate cancer cells.
Ishikura, Nobuyuki; Kawata, Hiromitsu; Nishimoto, Ayako; Nakamura, Ryo; Tsunenari, Toshiaki; Watanabe, Miho; Tachibana, Kazutaka; Shiraishi, Takuya; Yoshino, Hitoshi; Honma, Akie; Emura, Takashi; Ohta, Masateru; Nakagawa, Toshito; Houjo, Takao; Corey, Eva; Vessella, Robert L; Aoki, Yuko; Sato, Haruhiko.
Affiliation
  • Ishikura N; Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan.
  • Kawata H; Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan.
  • Nishimoto A; Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan.
  • Nakamura R; Chugai Research Institute for Medical Science, Inc., Kamakura, Kanagawa 247-8530, Japan.
  • Tsunenari T; Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan.
  • Watanabe M; Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan.
  • Tachibana K; Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan.
  • Shiraishi T; Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan.
  • Yoshino H; Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan.
  • Honma A; Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan.
  • Emura T; Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan.
  • Ohta M; Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan.
  • Nakagawa T; Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan.
  • Houjo T; Chugai Research Institute for Medical Science, Inc., Kamakura, Kanagawa 247-8530, Japan.
  • Corey E; Department of Urology, University of Washington, Seattle, WA 98195, USA.
  • Vessella RL; Department of Urology, University of Washington, Seattle, WA 98195, USA.
  • Aoki Y; Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan.
  • Sato H; Research Division, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa 247-8530, Japan.
Int J Oncol ; 46(4): 1560-72, 2015 Apr.
Article in En | MEDLINE | ID: mdl-25634071
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Thiohydantoins / Receptors, Androgen / Prostate-Specific Antigen / Prostatic Neoplasms, Castration-Resistant / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Int J Oncol Journal subject: NEOPLASIAS Year: 2015 Type: Article Affiliation country: Japan
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Thiohydantoins / Receptors, Androgen / Prostate-Specific Antigen / Prostatic Neoplasms, Castration-Resistant / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Int J Oncol Journal subject: NEOPLASIAS Year: 2015 Type: Article Affiliation country: Japan