The human platelet alloantigens, PlA1 and PlA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing.

Newman, P J; Derbes, R S; Aster, R H

Newman, P J; Derbes, R S; Aster, R H.

Affiliation

Newman PJ; Blood Center of Southeastern Wisconsin, Milwaukee 53233.

J Clin Invest ; 83(5): 1778-81, 1989 May.

Article in En | MEDLINE | ID: mdl-2565345

Subject(s)

Antigens, Human Platelet; DNA/analysis; Isoantigens/isolation & purification; Leucine; Platelet Membrane Glycoproteins/genetics; Polymorphism, Genetic; Proline; Amino Acid Sequence; Base Sequence; Homozygote; Humans; Integrin beta3; Isoantigens/genetics; Phenotype; Polymorphism, Restriction Fragment Length

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / DNA / Proline / Platelet Membrane Glycoproteins / Antigens, Human Platelet / Isoantigens / Leucine Type of study: Risk_factors_studies Limits: Humans Language: En Journal: J Clin Invest Year: 1989 Type: Article

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