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A coiled-coil mimetic intercepts BCR-ABL1 dimerization in native and kinase-mutant chronic myeloid leukemia.
Woessner, D W; Eiring, A M; Bruno, B J; Zabriskie, M S; Reynolds, K R; Miller, G D; O'Hare, T; Deininger, M W; Lim, C S.
Affiliation
  • Woessner DW; Department of Pharmacology and Toxicology, College of Pharmacy, The University of Utah, Salt Lake City, UT, USA.
  • Eiring AM; Huntsman Cancer Institute, The University of Utah, Salt Lake City, UT, USA.
  • Bruno BJ; Department of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The University of Utah, Salt Lake City, UT, USA.
  • Zabriskie MS; Huntsman Cancer Institute, The University of Utah, Salt Lake City, UT, USA.
  • Reynolds KR; Huntsman Cancer Institute, The University of Utah, Salt Lake City, UT, USA.
  • Miller GD; Department of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The University of Utah, Salt Lake City, UT, USA.
  • O'Hare T; 1] Huntsman Cancer Institute, The University of Utah, Salt Lake City, UT, USA [2] Division of Hematology and Hematologic Malignancies, The University of Utah, Salt Lake City, UT, USA.
  • Deininger MW; 1] Huntsman Cancer Institute, The University of Utah, Salt Lake City, UT, USA [2] Division of Hematology and Hematologic Malignancies, The University of Utah, Salt Lake City, UT, USA.
  • Lim CS; 1] Huntsman Cancer Institute, The University of Utah, Salt Lake City, UT, USA [2] Department of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The University of Utah, Salt Lake City, UT, USA.
Leukemia ; 29(8): 1668-75, 2015 Aug.
Article in En | MEDLINE | ID: mdl-25721898

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein-Tyrosine Kinases / Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Fusion Proteins, bcr-abl / Point Mutation / Drug Resistance, Neoplasm / Protein Multimerization Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2015 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein-Tyrosine Kinases / Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Fusion Proteins, bcr-abl / Point Mutation / Drug Resistance, Neoplasm / Protein Multimerization Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2015 Type: Article Affiliation country: United States