Tolerogenic modulation of the immune response by oligoglycerol- and polyglycerol-peptide conjugates.

Gupta, Shilpi; Pfeil, Jennifer; Kumar, Sumit; Poulsen, Christina; Lauer, Uta; Hamann, Alf; Hoffmann, Ute; Haag, Rainer

Gupta, Shilpi; Pfeil, Jennifer; Kumar, Sumit; Poulsen, Christina; Lauer, Uta; Hamann, Alf; Hoffmann, Ute; Haag, Rainer.

Affiliation

Gupta S; Organic and Macromolecular Chemistry, Department of Chemistry and Biochemistry, Free University Berlin, Takustrasse 3, 14195 Berlin, Germany.
Pfeil J; Department of Chemistry, Hindu College, Sonepat-131001, Haryana, India.
Kumar S; §Deutsches Rheuma-Forschungszentrum and Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Poulsen C; Organic and Macromolecular Chemistry, Department of Chemistry and Biochemistry, Free University Berlin, Takustrasse 3, 14195 Berlin, Germany.
Lauer U; â¥Department of Chemistry, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Sonepat-131039, Haryana, India.
Hamann A; §Deutsches Rheuma-Forschungszentrum and Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Hoffmann U; §Deutsches Rheuma-Forschungszentrum and Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Haag R; §Deutsches Rheuma-Forschungszentrum and Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.

Bioconjug Chem ; 26(4): 669-79, 2015 Apr 15.

Article in En | MEDLINE | ID: mdl-25757018

Subject(s)

Glycerol/chemistry; Immune Tolerance/drug effects; Immunologic Factors/pharmacology; Ovalbumin/chemistry; Peptides/chemistry; Polymers/chemistry; Adoptive Transfer; Amino Acid Sequence; Animals; Autoimmune Diseases/drug therapy; Autoimmune Diseases/immunology; Autoimmune Diseases/pathology; Biological Availability; Cells, Cultured; Dendritic Cells/cytology; Dendritic Cells/immunology; Forkhead Transcription Factors/genetics; Forkhead Transcription Factors/immunology; Gene Expression; Glycerol/analogs & derivatives; Glycerol/immunology; Immunologic Factors/chemistry; Immunologic Factors/immunology; Immunologic Factors/pharmacokinetics; Mice; Mice, Inbred BALB C; Mice, Transgenic; Molecular Sequence Data; Molecular Targeted Therapy; Ovalbumin/immunology; Peptides/immunology; Peptides/pharmacokinetics; Peptides/pharmacology; Receptors, Antigen, T-Cell/genetics; Receptors, Antigen, T-Cell/immunology; Structure-Activity Relationship; T-Lymphocytes, Regulatory/cytology; T-Lymphocytes, Regulatory/immunology; T-Lymphocytes, Regulatory/transplantation; Tumor Necrosis Factor-alpha/genetics; Tumor Necrosis Factor-alpha/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Polymers / Ovalbumin / Glycerol / Immune Tolerance / Immunologic Factors Language: En Journal: Bioconjug Chem Journal subject: BIOQUIMICA Year: 2015 Type: Article Affiliation country: Germany

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