Tumor-targeted and immune-targeted monoclonal antibodies: Going from passive to active immunotherapy.

Marabelle, Aurélien; Gray, Juliet

Marabelle, Aurélien; Gray, Juliet.

Affiliation

Marabelle A; Institut d' Hématologie et d'Oncologie Pédiatrique, Centre de Lutte contre le Cancer Léon Bérard, Lyon, France.
Gray J; Drug Development Department (DITEP), Gustave Roussy Cancer Campus, Villejuif, France.

Pediatr Blood Cancer ; 62(8): 1317-25, 2015 Aug.

Article in En | MEDLINE | ID: mdl-25808079

Subject(s)

Antibodies, Monoclonal/therapeutic use; Antineoplastic Agents/therapeutic use; Immunotherapy, Active/methods; Neoplasms/drug therapy; Adult; Child; Humans; Neoplasms/immunology; Tumor Escape/immunology

Key words

anti-CTLA-4; anti-PD-1; anti-PD-L1; immune checkpoint blockade; monoclonal antibodies; pediatric cancers

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunotherapy, Active / Antibodies, Monoclonal / Neoplasms / Antineoplastic Agents Limits: Adult / Child / Humans Language: En Journal: Pediatr Blood Cancer Journal subject: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Year: 2015 Type: Article Affiliation country: France

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