High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer.

Tan, Iain Beehuat; Malik, Simeen; Ramnarayanan, Kalpana; McPherson, John R; Ho, Dan Liang; Suzuki, Yuka; Ng, Sarah Boonhsui; Yan, Su; Lim, Kiat Hon; Koh, Dennis; Hoe, Chew Min; Chan, Chung Yip; Ten, Rachel; Goh, Brian Kp; Chung, Alexander Yf; Tan, Joanna; Chan, Cheryl Xueli; Tay, Su Ting; Alexander, Lezhava; Nagarajan, Niranjan; Hillmer, Axel M; Tang, Choon Leong; Chua, Clarinda; Teh, Bin Tean; Rozen, Steve; Tan, Patrick

Tan, Iain Beehuat; Malik, Simeen; Ramnarayanan, Kalpana; McPherson, John R; Ho, Dan Liang; Suzuki, Yuka; Ng, Sarah Boonhsui; Yan, Su; Lim, Kiat Hon; Koh, Dennis; Hoe, Chew Min; Chan, Chung Yip; Ten, Rachel; Goh, Brian Kp; Chung, Alexander Yf; Tan, Joanna; Chan, Cheryl Xueli; Tay, Su Ting; Alexander, Lezhava; Nagarajan, Niranjan; Hillmer, Axel M; Tang, Choon Leong; Chua, Clarinda; Teh, Bin Tean; Rozen, Steve; Tan, Patrick.

Genome Biol ; 16: 32, 2015 Feb 12.

Article in En | MEDLINE | ID: mdl-25808843

Subject(s)

Colorectal Neoplasms/genetics; Disease Progression; Genes, Neoplasm; High-Throughput Nucleotide Sequencing/methods; Liver Neoplasms/genetics; Liver Neoplasms/secondary; Algorithms; Alleles; Allelic Imbalance/genetics; Base Sequence; Colorectal Neoplasms/drug therapy; Colorectal Neoplasms/pathology; Computational Biology; Gene Frequency/genetics; Genome, Human; Humans; Liver Neoplasms/drug therapy; Molecular Sequence Data; Mutation/genetics; Neoplasms, Multiple Primary/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Disease Progression / Genes, Neoplasm / High-Throughput Nucleotide Sequencing / Liver Neoplasms Limits: Humans Language: En Journal: Genome Biol Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2015 Type: Article

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