[(13)C3,(15)N1]-labeled isodesmosine: A potential internal standard for LC-MS/MS analysis of desmosines in elastin degradation.

Tanigawa, Takahiro; Komatsu, Akira; Usuki, Toyonobu

Tanigawa, Takahiro; Komatsu, Akira; Usuki, Toyonobu.

Affiliation

Tanigawa T; Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioicho, Chiyoda-ku, Tokyo 102-8554, Japan.
Komatsu A; Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioicho, Chiyoda-ku, Tokyo 102-8554, Japan.
Usuki T; Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioicho, Chiyoda-ku, Tokyo 102-8554, Japan. Electronic address: t-usuki@sophia.ac.jp.

Bioorg Med Chem Lett ; 25(10): 2046-9, 2015.

Article in En | MEDLINE | ID: mdl-25890800

Subject(s)

Chromatography, Liquid; Desmosine/analysis; Elastin/metabolism; Isodesmosine/chemical synthesis; Tandem Mass Spectrometry; Biomarkers/metabolism; Carbon Isotopes/analysis; Elastin/chemistry; Isodesmosine/chemistry; Molecular Structure; Nitrogen Isotopes/analysis; Pulmonary Disease, Chronic Obstructive/pathology

Key words

Biomarker; Chichibabin pyridine synthesis; Elastin degradation; Isodesmosine; Isotopic label

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatography, Liquid / Elastin / Desmosine / Tandem Mass Spectrometry / Isodesmosine Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2015 Type: Article Affiliation country: Japan

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