Enhanced fitness and renal function in Type 2 diabetes.
Diabet Med
; 32(10): 1342-5, 2015 Oct.
Article
in En
| MEDLINE
| ID: mdl-25943475
ABSTRACT
AIMS:
To investigate the renal effects of fitness in people with diabetes with mild renal dysfunction.METHODS:
The effect of a 12-week exercise programme on estimated GFR in 128 people with diabetes was evaluated.RESULTS:
All cardiometabolic variables improved after 12 weeks of supervised exercise. Although there was a modest 3.9% increase in estimated GFR from baseline in the 128 people who completed the study, those with baseline chronic kidney disease stages 2 and 3 were found to have significant (6 and 12%, respectively; p < 0.01) improvements in post-exercise estimated GFR. Moreover, 42% of the people with chronic kidney disease stage 3 improved to chronic kidney disease stage 2 after the intervention.CONCLUSION:
Short-term exercise improves renal function in those with more moderate baseline chronic kidney disease. Thus, renal function appears to be responsive to enhanced physical fitness. Being a strong and modifiable risk factor, enhanced fitness should be considered a non-pharmacological adjunct in the management of diabetic kidney disease.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Physical Fitness
/
Diabetes Mellitus, Type 2
/
Diabetic Nephropathies
/
Renal Insufficiency, Chronic
/
Kidney
Type of study:
Risk_factors_studies
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Diabet Med
Journal subject:
ENDOCRINOLOGIA
Year:
2015
Type:
Article
Affiliation country:
United States