Does platelet-rich plasma enhance healing in the idiopathic bone cavity? A single-blind randomized clinical trial.
Int J Oral Maxillofac Surg
; 44(9): 1175-80, 2015 Sep.
Article
in En
| MEDLINE
| ID: mdl-26074365
ABSTRACT
The presence of an idiopathic bone cavity (IBC) is usually identified during routine dental radiographic examinations. The purpose of this study was to investigate the effect of platelet-rich plasma (PRP) on bone healing in the idiopathic bone cavity. This was a single-blind randomized clinical trial. Twenty-four subjects were assigned randomly to two groups. Subjects in group 1 received PRP through a buccal window approach, and those in group 2 underwent conventional management via the creation of a window on the buccal wall and curettage of the walls of the defect. Subjects were followed up at 3, 6, and 9 months after the intervention. The amount of bone formation as determined on panoramic radiographs was divided into four categories stage 1 ≤25% of the defect showed opacity; stage 2 25-50% of the defect showed opacity; stage 3 50-75% of the defect showed opacity; and stage 4 >75% of the defect showed opacity. There was a significant difference between the two groups with regard to the various healing stages at the three time points (P<0.05). When compared with conventional management of the idiopathic bone cavity, the use of PRP may enhance bone formation.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Wound Healing
/
Bone Regeneration
/
Alveolar Bone Loss
/
Platelet-Rich Plasma
Type of study:
Clinical_trials
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
Int J Oral Maxillofac Surg
Journal subject:
ODONTOLOGIA
Year:
2015
Type:
Article