The calcium-sensing receptor and integrins modulate cerebellar granule cell precursor differentiation and migration.

Tharmalingam, Sujeenthar; Wu, Chiping; Hampson, David R

Tharmalingam, Sujeenthar; Wu, Chiping; Hampson, David R.

Affiliation

Tharmalingam S; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada, M5S 3M2.
Wu C; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada, M5S 3M2.
Hampson DR; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada, M5S 3M2.

Dev Neurobiol ; 76(4): 375-89, 2016 Apr.

Article in En | MEDLINE | ID: mdl-26138678

Subject(s)

Cell Movement/physiology; Cerebellum/metabolism; Integrin beta1/metabolism; Neural Stem Cells/metabolism; Neurogenesis/physiology; Receptors, Calcium-Sensing/metabolism; Allosteric Regulation/drug effects; Allosteric Regulation/physiology; Animals; Calcium/metabolism; Cell Membrane/drug effects; Cell Membrane/metabolism; Cell Movement/drug effects; Cells, Cultured; Cerebellum/cytology; Cerebellum/drug effects; Cerebellum/growth & development; Laminin/metabolism; Neural Stem Cells/cytology; Neural Stem Cells/drug effects; Neurogenesis/drug effects; Neurons/cytology; Neurons/drug effects; Neurons/metabolism; Phosphorylation/physiology; Proto-Oncogene Proteins c-akt/antagonists & inhibitors; Proto-Oncogene Proteins c-akt/metabolism; Rats, Sprague-Dawley

Key words

Bergmann glia; G-protein coupled receptor; Purkinje cell; adhesion; cerebellum; granule cell precursor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Movement / Cerebellum / Integrin beta1 / Receptors, Calcium-Sensing / Neurogenesis / Neural Stem Cells Limits: Animals Language: En Journal: Dev Neurobiol Journal subject: BIOLOGIA / NEUROLOGIA Year: 2016 Type: Article

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