High proportion of MERS-CoV shedding dromedaries at slaughterhouse with a potential epidemiological link to human cases, Qatar 2014.
Infect Ecol Epidemiol
; 5: 28305, 2015.
Article
in En
| MEDLINE
| ID: mdl-26183160
ABSTRACT
Two of the earliest Middle East respiratory syndrome (MERS) cases were men who had visited the Doha central animal market and adjoining slaughterhouse in Qatar. We show that a high proportion of camels presenting for slaughter in Qatar show evidence for nasal MERS-CoV shedding (62/105). Sequence analysis showed the circulation of at least five different virus strains at these premises, suggesting that this location is a driver of MERS-CoV circulation and a high-risk area for human exposure. No correlation between RNA loads and levels of neutralizing antibodies was observed, suggesting limited immune protection and potential for reinfection despite previous exposure.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Infect Ecol Epidemiol
Year:
2015
Type:
Article
Affiliation country:
Qatar