The common PNPLA3 variant p.I148M is associated with liver fat contents as quantified by controlled attenuation parameter (CAP).

Arslanow, Anita; Stokes, Caroline S; Weber, Susanne N; Grünhage, Frank; Lammert, Frank; Krawczyk, Marcin

Arslanow, Anita; Stokes, Caroline S; Weber, Susanne N; Grünhage, Frank; Lammert, Frank; Krawczyk, Marcin.

Affiliation

Arslanow A; Department of Medicine II, Saarland University Medical Center, Homburg, Germany.
Stokes CS; Department of Medicine II, Saarland University Medical Center, Homburg, Germany.
Weber SN; Department of Medicine II, Saarland University Medical Center, Homburg, Germany.
Grünhage F; Department of Medicine II, Saarland University Medical Center, Homburg, Germany.
Lammert F; Department of Medicine II, Saarland University Medical Center, Homburg, Germany.
Krawczyk M; Department of Medicine II, Saarland University Medical Center, Homburg, Germany.

Liver Int ; 36(3): 418-26, 2016 Mar.

Article in En | MEDLINE | ID: mdl-26264356

Subject(s)

Adiposity/genetics; Lipase/genetics; Liver/pathology; Membrane Proteins/genetics; Non-alcoholic Fatty Liver Disease/genetics; Polymorphism, Genetic; Adolescent; Adult; Aged; Body Mass Index; Case-Control Studies; Elasticity Imaging Techniques; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Linear Models; Logistic Models; Male; Middle Aged; Multivariate Analysis; Non-alcoholic Fatty Liver Disease/diagnosis; Non-alcoholic Fatty Liver Disease/enzymology; Non-alcoholic Fatty Liver Disease/pathology; Odds Ratio; Phenotype; Prognosis; Risk Assessment; Risk Factors; Young Adult

Key words

TM6SF2; adiponutrin; elastography; non-alcoholic fatty liver disease

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Adiposity / Non-alcoholic Fatty Liver Disease / Lipase / Liver / Membrane Proteins Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Liver Int Journal subject: GASTROENTEROLOGIA Year: 2016 Type: Article Affiliation country: Germany

Fulltext

XML

PubMed Links

Search on Google