Simple accurate mathematical models of blood HbO2 and HbCO2 dissociation curves at varied physiological conditions: evaluation and comparison with other models.

Dash, Ranjan K; Korman, Ben; Bassingthwaighte, James B

Dash, Ranjan K; Korman, Ben; Bassingthwaighte, James B.

Affiliation

Dash RK; Department of Physiology, Biotechnology and Bioengineering Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA. rdash@mcw.edu.
Korman B; Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, WA, Australia. ben@korman.com.au.
Bassingthwaighte JB; Department of Bioengineering, University of Washington, Box 355061, N210G North Foege Bldg, Seattle, WA, 9895-5061, USA. jbb2@u.washington.edu.

Eur J Appl Physiol ; 116(1): 97-113, 2016 Jan.

Article in En | MEDLINE | ID: mdl-26298270

Subject(s)

Carbon Dioxide/blood; Hemoglobins/metabolism; Oxygen/blood; Oxyhemoglobins/metabolism; Temperature; Hemoglobin A/analogs & derivatives; Hemoglobin A/metabolism; Humans; Hydrogen-Ion Concentration; Models, Biological

Key words

Bohr and Haldane effects; Mathematical modeling; Nonlinear O2CO2 interactions; O2 and CO2 binding to hemoglobin; O2 and CO2 saturation of hemoglobin; Oxyhemoglobin and carbaminohemoglobin dissociation curves

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxygen / Temperature / Hemoglobins / Oxyhemoglobins / Carbon Dioxide Type of study: Prognostic_studies Limits: Humans Language: En Journal: Eur J Appl Physiol Journal subject: FISIOLOGIA Year: 2016 Type: Article Affiliation country: United States

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