Next Generation of SiFAlin-Based TATE Derivatives for PET Imaging of SSTR-Positive Tumors: Influence of Molecular Design on In Vitro SSTR Binding and In Vivo Pharmacokinetics.

Litau, S; Niedermoser, S; Vogler, N; Roscher, M; Schirrmacher, R; Fricker, G; Wängler, B; Wängler, C

Litau, S; Niedermoser, S; Vogler, N; Roscher, M; Schirrmacher, R; Fricker, G; Wängler, B; Wängler, C.

Affiliation

Schirrmacher R; Department of Oncology, Division of Oncological Imaging, University of Alberta , Edmonton T6G 2R3, Canada.
Fricker G; Institute of Pharmacy and Molecular Biotechnology, University of Heidelberg , 69117 Heidelberg, Germany.

Bioconjug Chem ; 26(12): 2350-9, 2015 Dec 16.

Article in En | MEDLINE | ID: mdl-26420336

Subject(s)

Fluorides/metabolism; Fluorine Radioisotopes/metabolism; Neoplasms/diagnostic imaging; Peptides, Cyclic/metabolism; Positron-Emission Tomography/methods; Receptors, Somatostatin/metabolism; Silicon/metabolism; Animals; Cell Line; Cell Line, Tumor; Fluorides/chemistry; Fluorides/pharmacokinetics; Fluorine Radioisotopes/chemistry; Fluorine Radioisotopes/pharmacokinetics; Humans; Mice, Nude; Models, Molecular; Neoplasms/diagnosis; Neoplasms/metabolism; Peptides, Cyclic/chemistry; Peptides, Cyclic/pharmacokinetics; Silicon/chemistry; Silicon/pharmacokinetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides, Cyclic / Silicon / Fluorine Radioisotopes / Receptors, Somatostatin / Positron-Emission Tomography / Fluorides / Neoplasms Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioconjug Chem Journal subject: BIOQUIMICA Year: 2015 Type: Article

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