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Lack of Gαi2 leads to dilative cardiomyopathy and increased mortality in ß1-adrenoceptor overexpressing mice.
Keller, Kirsten; Maass, Martina; Dizayee, Sara; Leiss, Veronika; Annala, Suvi; Köth, Jessica; Seemann, Wiebke K; Müller-Ehmsen, Jochen; Mohr, Klaus; Nürnberg, Bernd; Engelhardt, Stefan; Herzig, Stefan; Birnbaumer, Lutz; Matthes, Jan.
Affiliation
  • Keller K; Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Cologne, Germany.
  • Maass M; Department of Internal Medicine III, University Hospital of Cologne, Cologne, Germany.
  • Dizayee S; Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Cologne, Germany.
  • Leiss V; Department of Pharmacology and Experimental Therapy, Institute of Experimental and Clinical Pharmacology and Toxicology, Eberhard Karls University Hospitals and Clinics, and Interfaculty Center of Pharmacogenomics and Drug Research, Tuebingen, Germany.
  • Annala S; Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Cologne, Germany.
  • Köth J; Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Cologne, Germany.
  • Seemann WK; Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Cologne, Germany.
  • Müller-Ehmsen J; Asklepios Klinik Altona, Hamburg, Germany.
  • Mohr K; Pharmacology and Toxicology Section, Institute of Pharmacy, University of Bonn, Bonn, Germany.
  • Nürnberg B; Department of Pharmacology and Experimental Therapy, Institute of Experimental and Clinical Pharmacology and Toxicology, Eberhard Karls University Hospitals and Clinics, and Interfaculty Center of Pharmacogenomics and Drug Research, Tuebingen, Germany.
  • Engelhardt S; Institute of Pharmacology and Toxicology, Technische Universität München, Munich, Germany.
  • Herzig S; Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Cologne, Germany.
  • Birnbaumer L; Laboratory of Neurobiology, NIEHS, NIH (Department of Health and Human Services), Durham, USA.
  • Matthes J; Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Cologne, Germany jan.matthes@uni-koeln.de.
Cardiovasc Res ; 108(3): 348-56, 2015 Dec 01.
Article in En | MEDLINE | ID: mdl-26464333
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiomyopathy, Dilated / Receptors, Adrenergic, beta-1 / Myocytes, Cardiac / GTP-Binding Protein alpha Subunit, Gi2 / Heart Failure Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Cardiovasc Res Year: 2015 Type: Article Affiliation country: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiomyopathy, Dilated / Receptors, Adrenergic, beta-1 / Myocytes, Cardiac / GTP-Binding Protein alpha Subunit, Gi2 / Heart Failure Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Cardiovasc Res Year: 2015 Type: Article Affiliation country: Germany