Population Pharmacokinetics of Amitriptyline After Intrathecal, Epidural, and Intravenous Administration in Sheep.

Ratajczak-Enselme, Maja; Grégoire, Nicolas; Estebe, Jean-Pierre; Dollo, Gilles; Chevanne, F; Bec, David; Ecoffey, Claude; Couet, William; Le Corre, Pascal

Ratajczak-Enselme, Maja; Grégoire, Nicolas; Estebe, Jean-Pierre; Dollo, Gilles; Chevanne, F; Bec, David; Ecoffey, Claude; Couet, William; Le Corre, Pascal.

Affiliation

Ratajczak-Enselme M; From the *Faculté des Sciences Pharmaceutiques et Biologiques, Université de Rennes 1, and INSERM U1085; and Service Hospitalo-Universitaire de Pharmacie, CHU Rennes, Rennes; INSERM U1070 and Faculté de Médecine et de Pharmacie, Université de Poitiers, Poitiers; and §Département d'Anesthésie 2, Faculté de Médecine, Université de Rennes 1, Rennes, France.

Reg Anesth Pain Med ; 40(6): 681-6, 2015.

Article in En | MEDLINE | ID: mdl-26469370

Subject(s)

Amitriptyline/administration & dosage; Amitriptyline/pharmacokinetics; Analgesics, Non-Narcotic/administration & dosage; Analgesics, Non-Narcotic/pharmacokinetics; Epidural Space/metabolism; Administration, Intravenous; Analgesia, Epidural/methods; Animals; Epidural Space/drug effects; Female; Injections, Epidural; Injections, Spinal; Sheep

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Analgesics, Non-Narcotic / Epidural Space / Amitriptyline Limits: Animals Language: En Journal: Reg Anesth Pain Med Journal subject: ANESTESIOLOGIA / NEUROLOGIA / PSICOFISIOLOGIA Year: 2015 Type: Article Affiliation country: France

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