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A global initiative to refine acute inhalation studies through the use of 'evident toxicity' as an endpoint: Towards adoption of the fixed concentration procedure.
Sewell, Fiona; Ragan, Ian; Marczylo, Tim; Anderson, Brian; Braun, Anne; Casey, Warren; Dennison, Ngaire; Griffiths, David; Guest, Robert; Holmes, Tom; van Huygevoort, Ton; Indans, Ian; Kenny, Terry; Kojima, Hajime; Lee, Kyuhong; Prieto, Pilar; Smith, Paul; Smedley, Jason; Stokes, William S; Wnorowski, Gary; Horgan, Graham.
Affiliation
  • Sewell F; NC3Rs, UK. Electronic address: fiona.sewell@nc3rs.org.uk.
  • Ragan I; Board Member, NC3Rs, UK.
  • Marczylo T; Public Health England, UK.
  • Anderson B; Harlan Laboratories, Switzerland.
  • Braun A; INERIS, France.
  • Casey W; NICEATM, USA.
  • Dennison N; Home Office, UK.
  • Griffiths D; Harlan Laboratories, UK.
  • Guest R; Harlan Laboratories, UK.
  • Holmes T; Exponent International Limited, UK.
  • van Huygevoort T; WIL Research, The Netherlands.
  • Indans I; Health and Safety Executive, UK.
  • Kenny T; Huntingdon Life Sciences, UK.
  • Kojima H; JaCVAM (Japanese Center for the Validation of Alternative Methods), NIHS (National Institute of Health Sciences), Japan.
  • Lee K; Korea Institute of Toxicology, South Korea.
  • Prieto P; EURL ECVAM, Systems Toxicology Unit, Institute for Health and Consumer Protection, European Commission, Joint Research Centre, Ispra, Italy.
  • Smith P; Charles River Laboratories, Edinburgh, UK.
  • Smedley J; Charles River Laboratories, OH, USA.
  • Stokes WS; U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Animal Care, USA.
  • Wnorowski G; Product Safety Laboratories, USA.
  • Horgan G; BioSS, UK.
Regul Toxicol Pharmacol ; 73(3): 770-9, 2015 Dec.
Article in En | MEDLINE | ID: mdl-26505531
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inhalation Exposure / Endpoint Determination / Toxicity Tests, Acute / International Cooperation Type of study: Guideline / Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Regul Toxicol Pharmacol Year: 2015 Type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inhalation Exposure / Endpoint Determination / Toxicity Tests, Acute / International Cooperation Type of study: Guideline / Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Regul Toxicol Pharmacol Year: 2015 Type: Article