Sufficient dimension reduction with additional information.
Biostatistics
; 17(3): 405-21, 2016 07.
Article
in En
| MEDLINE
| ID: mdl-26704765
ABSTRACT
Sufficient dimension reduction is widely applied to help model building between the response [Formula see text] and covariate [Formula see text] In some situations, we also collect additional covariate [Formula see text] that has better performance in predicting [Formula see text], but has a higher obtaining cost, than [Formula see text] While constructing a predictive model for [Formula see text] based on [Formula see text] is straightforward, this strategy is not applicable since [Formula see text] is not available for future observations in which the constructed model is to be applied. As a result, the aim of the study is to build a predictive model for [Formula see text] based on [Formula see text] only, where the available data is [Formula see text] A naive method is to conduct analysis using [Formula see text] directly, but ignoring [Formula see text] can cause the problem of inefficiency. On the other hand, it is not trivial to utilize the information of [Formula see text] to infer [Formula see text], either. In this article, we propose a two-stage dimension reduction method for [Formula see text] that is able to utilize the information of [Formula see text] In the breast cancer data, the risk score constructed from the two-stage method can well separate patients with different survival experiences. In the Pima data, the two-stage method requires fewer components to infer the diabetes status, while achieving higher classification accuracy than the conventional method.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Data Interpretation, Statistical
/
Risk Assessment
/
Models, Theoretical
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
Country/Region as subject:
America do norte
Language:
En
Journal:
Biostatistics
Year:
2016
Type:
Article
Affiliation country:
Taiwan