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Sunitinib-induced hypertension in CYP3A4 rs4646437 A-allele carriers with metastatic renal cell carcinoma.
Diekstra, M H; Belaustegui, A; Swen, J J; Boven, E; Castellano, D; Gelderblom, H; Mathijssen, R H; García-Donas, J; Rodríguez-Antona, C; Rini, B I; Guchelaar, H-J.
Affiliation
  • Diekstra MH; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
  • Belaustegui A; Dutch Working Group Focusing on Genotype-related Sunitinib-induced Toxicity (SUTOX Consortium), Leiden, The Netherlands.
  • Swen JJ; Department of Clinical Pharmacy, Hospital Universitario Cruces, Barakaldo, Bizkaia, Spain.
  • Boven E; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
  • Castellano D; Dutch Working Group Focusing on Genotype-related Sunitinib-induced Toxicity (SUTOX Consortium), Leiden, The Netherlands.
  • Gelderblom H; Dutch Working Group Focusing on Genotype-related Sunitinib-induced Toxicity (SUTOX Consortium), Leiden, The Netherlands.
  • Mathijssen RH; Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands.
  • García-Donas J; Oncology Department, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Rodríguez-Antona C; Spanish Oncology Genitourinary Group, Madrid, Spain.
  • Rini BI; Dutch Working Group Focusing on Genotype-related Sunitinib-induced Toxicity (SUTOX Consortium), Leiden, The Netherlands.
  • Guchelaar HJ; Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands.
Pharmacogenomics J ; 17(1): 42-46, 2017 01.
Article in En | MEDLINE | ID: mdl-26810136
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Carcinoma, Renal Cell / Angiogenesis Inhibitors / Polymorphism, Single Nucleotide / Protein Kinase Inhibitors / Cytochrome P-450 CYP3A / Pharmacogenomic Variants / Hypertension / Indoles / Kidney Neoplasms Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged80 Country/Region as subject: America do norte / Europa Language: En Journal: Pharmacogenomics J Journal subject: BIOLOGIA MOLECULAR / FARMACOLOGIA Year: 2017 Type: Article Affiliation country: Netherlands
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Carcinoma, Renal Cell / Angiogenesis Inhibitors / Polymorphism, Single Nucleotide / Protein Kinase Inhibitors / Cytochrome P-450 CYP3A / Pharmacogenomic Variants / Hypertension / Indoles / Kidney Neoplasms Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged80 Country/Region as subject: America do norte / Europa Language: En Journal: Pharmacogenomics J Journal subject: BIOLOGIA MOLECULAR / FARMACOLOGIA Year: 2017 Type: Article Affiliation country: Netherlands