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The Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator ADX88178 Inhibits Inflammatory Responses in Primary Microglia.
Ponnazhagan, Ranjani; Harms, Ashley S; Thome, Aaron D; Jurkuvenaite, Asta; Gogliotti, Rocco; Niswender, Colleen M; Conn, P Jeffrey; Standaert, David G.
Affiliation
  • Ponnazhagan R; Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
  • Harms AS; Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
  • Thome AD; Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
  • Jurkuvenaite A; Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
  • Gogliotti R; Vanderbilt Center for Neuroscience Drug Discovery, Department of Pharmacology, Vanderbilt Kennedy Center, Vanderbilt University, Nashville, TN, 37235, USA.
  • Niswender CM; Vanderbilt Center for Neuroscience Drug Discovery, Department of Pharmacology, Vanderbilt Kennedy Center, Vanderbilt University, Nashville, TN, 37235, USA.
  • Conn PJ; Vanderbilt Center for Neuroscience Drug Discovery, Department of Pharmacology, Vanderbilt Kennedy Center, Vanderbilt University, Nashville, TN, 37235, USA.
  • Standaert DG; Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA. dstandaert@uab.edu.
J Neuroimmune Pharmacol ; 11(2): 231-7, 2016 06.
Article in En | MEDLINE | ID: mdl-26872456
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Thiazoles / Receptors, Metabotropic Glutamate / Microglia / Inflammation Mediators / Anti-Inflammatory Agents Limits: Animals Language: En Journal: J Neuroimmune Pharmacol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA / NEUROLOGIA Year: 2016 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Thiazoles / Receptors, Metabotropic Glutamate / Microglia / Inflammation Mediators / Anti-Inflammatory Agents Limits: Animals Language: En Journal: J Neuroimmune Pharmacol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA / NEUROLOGIA Year: 2016 Type: Article Affiliation country: United States