Mitochondrial N-formyl peptides cause airway contraction and lung neutrophil infiltration via formyl peptide receptor activation.

Wenceslau, Camilla Ferreira; Szasz, Theodora; McCarthy, Cameron G; Baban, Babak; NeSmith, Elizabeth; Webb, R Clinton

Wenceslau, Camilla Ferreira; Szasz, Theodora; McCarthy, Cameron G; Baban, Babak; NeSmith, Elizabeth; Webb, R Clinton.

Affiliation

Wenceslau CF; Department of Physiology, Augusta University, Augusta, GA, USA. Electronic address: camillawenceslau@hotmail.com.
Szasz T; Department of Physiology, Augusta University, Augusta, GA, USA.
McCarthy CG; Department of Physiology, Augusta University, Augusta, GA, USA.
Baban B; Department of Oral Biology, Augusta University, Augusta, GA, USA.
NeSmith E; Department of Physiological & Technological Nursing, Augusta University, Augusta, GA, USA.
Webb RC; Department of Physiology, Augusta University, Augusta, GA, USA.

Pulm Pharmacol Ther ; 37: 49-56, 2016 04.

Article in En | MEDLINE | ID: mdl-26923940

Subject(s)

Mitochondria/metabolism; N-Formylmethionine Leucyl-Phenylalanine/metabolism; Neutrophil Infiltration/physiology; Receptors, Formyl Peptide/metabolism; Adolescent; Adult; Animals; Humans; Lung Injury/physiopathology; Male; Mast Cells/drug effects; Mast Cells/metabolism; Neutrophils/metabolism; Rats; Rats, Wistar; Respiratory Insufficiency/physiopathology; Sepsis/physiopathology; Systemic Inflammatory Response Syndrome/physiopathology; Young Adult

Key words

Airway and lung inflammation; Mitochondrial N-formyl peptides; Trauma

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neutrophil Infiltration / Receptors, Formyl Peptide / Mitochondria / N-Formylmethionine Leucyl-Phenylalanine Limits: Adolescent / Adult / Animals / Humans / Male Language: En Journal: Pulm Pharmacol Ther Journal subject: FARMACOLOGIA Year: 2016 Type: Article

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