Stability and Biodistribution of Thiol-Functionalized and (177)Lu-Labeled Metal Chelating Polymers Bound to Gold Nanoparticles.

Yook, Simmyung; Lu, Yijie; Jeong, Jenny Jooyoung; Cai, Zhongli; Tong, Lemuel; Alwarda, Ramina; Pignol, Jean-Philippe; Winnik, Mitchell A; Reilly, Raymond M

Yook, Simmyung; Lu, Yijie; Jeong, Jenny Jooyoung; Cai, Zhongli; Tong, Lemuel; Alwarda, Ramina; Pignol, Jean-Philippe; Winnik, Mitchell A; Reilly, Raymond M.

Affiliation

Pignol JP; Department of Radiation Oncology, Erasmus MC Cancer Institute , Rotterdam, The Netherlands.
Reilly RM; Toronto General Research Institute and Joint Department of Medical Imaging, University Health Network , Toronto, Ontario, Canada.

Biomacromolecules ; 17(4): 1292-302, 2016 Apr 11.

Article in En | MEDLINE | ID: mdl-26974228

Subject(s)

Beta Particles/therapeutic use; Breast Neoplasms/radiotherapy; Lutetium/therapeutic use; Nanomedicine/methods; Radioisotopes/therapeutic use; Radiopharmaceuticals/therapeutic use; Animals; Female; Gold/chemistry; Heterocyclic Compounds, 1-Ring/chemistry; Humans; Lutetium/chemistry; Metal Nanoparticles/chemistry; Metal Nanoparticles/therapeutic use; Mice; Mice, Nude; Polymers/chemical synthesis; Polymers/chemistry; Polymers/therapeutic use; Radioisotopes/chemistry; Sulfhydryl Compounds/chemistry

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radioisotopes / Beta Particles / Breast Neoplasms / Radiopharmaceuticals / Nanomedicine / Lutetium Limits: Animals / Female / Humans Language: En Journal: Biomacromolecules Journal subject: BIOLOGIA MOLECULAR Year: 2016 Type: Article

Fulltext

XML

PubMed Links

Search on Google