Urinary Concentrations and Antibacterial Activity of BAL30072, a Novel Siderophore Monosulfactam, against Uropathogens after Intravenous Administration in Healthy Subjects.

Straubinger, Marion; Blenk, Holger; Naber, Kurt G; Wagenlehner, Florian M E

Straubinger, Marion; Blenk, Holger; Naber, Kurt G; Wagenlehner, Florian M E.

Affiliation

Straubinger M; Prokaryon Institute, Nuremberg, Germany.
Blenk H; Prokaryon Institute, Nuremberg, Germany.
Naber KG; Technical University, Munich, Germany kurt.naber@nabers.de.
Wagenlehner FM; Department of Urology, Pediatric Urology and Andrology of the Justus Liebig University, Giessen, Germany.

Antimicrob Agents Chemother ; 60(6): 3309-15, 2016 06.

Article in En | MEDLINE | ID: mdl-26976871

Subject(s)

Anti-Bacterial Agents/therapeutic use; Anti-Bacterial Agents/urine; Monobactams/therapeutic use; Monobactams/urine; Thiazoles/therapeutic use; Thiazoles/urine; Urinary Tract Infections/drug therapy; Urinary Tract Infections/urine; Administration, Intravenous; Adult; Anti-Bacterial Agents/administration & dosage; Chromatography, Liquid; Enterobacteriaceae/drug effects; Enterobacteriaceae/pathogenicity; Escherichia coli/drug effects; Escherichia coli/pathogenicity; Healthy Volunteers; Humans; Klebsiella pneumoniae/drug effects; Klebsiella pneumoniae/pathogenicity; Male; Microbial Sensitivity Tests; Middle Aged; Monobactams/administration & dosage; Proteus mirabilis/drug effects; Proteus mirabilis/pathogenicity; Tandem Mass Spectrometry; Thiazoles/administration & dosage; Urinary Tract Infections/microbiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Urinary Tract Infections / Monobactams / Anti-Bacterial Agents Limits: Adult / Humans / Male / Middle aged Language: En Journal: Antimicrob Agents Chemother Year: 2016 Type: Article Affiliation country: Germany

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