Role of DNA breakage in cytotoxicity of doxorubicin, 9-deoxydoxorubicin, and 4-demethyl-6-deoxydoxorubicin in murine leukemia P388 cells.

Capranico, G; De Isabella, P; Penco, S; Tinelli, S; Zunino, F

Capranico, G; De Isabella, P; Penco, S; Tinelli, S; Zunino, F.

Affiliation

Capranico G; Division of Experimental Oncology B, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy.

Cancer Res ; 49(8): 2022-7, 1989 Apr 15.

Article in En | MEDLINE | ID: mdl-2702645

Subject(s)

DNA Damage; DNA/drug effects; Doxorubicin/analogs & derivatives; Doxorubicin/pharmacology; Leukemia P388/pathology; Leukemia, Experimental/pathology; Animals; Cell Survival/drug effects; DNA, Single-Stranded/drug effects; Doxorubicin/pharmacokinetics; Mice; Structure-Activity Relationship

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / DNA / Leukemia, Experimental / Leukemia P388 / Doxorubicin Limits: Animals Language: En Journal: Cancer Res Year: 1989 Type: Article Affiliation country: Italy

Search on Google

XML

PubMed Links