Aortic Aneurysm, Abdominal/metabolism; Epigenesis, Genetic; Extracellular Matrix Proteins/metabolism; Inflammation Mediators/metabolism; Muscle, Smooth, Vascular/drug effects; Myocytes, Smooth Muscle/drug effects; Recombinant Proteins/metabolism; Angiotensin II; Animals; Aorta, Abdominal/metabolism; Aorta, Abdominal/pathology; Aortic Aneurysm, Abdominal/chemically induced; Aortic Aneurysm, Abdominal/genetics; Aortic Aneurysm, Abdominal/pathology; Binding Sites; Case-Control Studies; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Down-Regulation; Epigenesis, Genetic/drug effects; Extracellular Matrix Proteins/genetics; Histone Deacetylase Inhibitors/pharmacology; Humans; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular/metabolism; Muscle, Smooth, Vascular/pathology; Myocytes, Smooth Muscle/metabolism; Myocytes, Smooth Muscle/pathology; Promoter Regions, Genetic; RNA Interference; Recombinant Proteins/genetics; SOX9 Transcription Factor/genetics; SOX9 Transcription Factor/metabolism; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha/metabolism

Abdominal aortic aneurysm; Fibulin-5; Histone deacetylases; SOX9; Vascular smooth muscle cells