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Reduced TCR-dependent activation through citrullination of a T-cell epitope enhances Th17 development by disruption of the STAT3/5 balance.
Tibbitt, Christopher; Falconer, Jane; Stoop, Jeroen; van Eden, Willem; Robinson, John H; Hilkens, Catharien M U.
Affiliation
  • Tibbitt C; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, U.K.
  • Falconer J; Rheumatology Research Group, School of Immunity and Infection, University of Birmingham, U.K.
  • Stoop J; Arthritis Research UK Rheumatoid Arthritis Pathogenesis Centre of Excellence (RACE), U.K.
  • van Eden W; Department of Rheumatology, Leiden University, The Netherlands.
  • Robinson JH; Institute of Infectious Diseases and Immunology, Utrecht University, The Netherlands.
  • Hilkens CM; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, U.K.
Eur J Immunol ; 46(7): 1633-43, 2016 07.
Article in En | MEDLINE | ID: mdl-27173727
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocyte Activation / Receptors, Antigen, T-Cell / Epitopes, T-Lymphocyte / STAT3 Transcription Factor / STAT5 Transcription Factor / Th17 Cells Limits: Animals Language: En Journal: Eur J Immunol Year: 2016 Type: Article Affiliation country: United kingdom
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocyte Activation / Receptors, Antigen, T-Cell / Epitopes, T-Lymphocyte / STAT3 Transcription Factor / STAT5 Transcription Factor / Th17 Cells Limits: Animals Language: En Journal: Eur J Immunol Year: 2016 Type: Article Affiliation country: United kingdom