Novel approaches to map small molecule-target interactions.

Kapoor, Shobhna; Waldmann, Herbert; Ziegler, Slava

Kapoor, Shobhna; Waldmann, Herbert; Ziegler, Slava.

Affiliation

Kapoor S; Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, Dortmund, Germany. Electronic address: shobhna.kapoor@mpi-dortmund.mpg.de.
Waldmann H; Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, Dortmund, Germany; Technical University Dortmund, Department of Chemistry and Chemical Biology, Otto-Hahn-Strasse 6, Dortmund, Germany.
Ziegler S; Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, Dortmund, Germany. Electronic address: slava.ziegler@mpi-dortmund.mpg.de.

Bioorg Med Chem ; 24(15): 3232-45, 2016 Aug 01.

Article in En | MEDLINE | ID: mdl-27240466

Subject(s)

Drug Discovery/methods; Molecular Targeted Therapy/methods; Small Molecule Libraries/chemistry; Small Molecule Libraries/pharmacology

Key words

Bioactive small molecules; CETSA, transcriptome sequencing; CRISPR/Cas9; Chem-seq; Profiling; Target identification; Target prediction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Small Molecule Libraries / Drug Discovery / Molecular Targeted Therapy Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2016 Type: Article

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