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Proteome-wide covalent ligand discovery in native biological systems.
Backus, Keriann M; Correia, Bruno E; Lum, Kenneth M; Forli, Stefano; Horning, Benjamin D; González-Páez, Gonzalo E; Chatterjee, Sandip; Lanning, Bryan R; Teijaro, John R; Olson, Arthur J; Wolan, Dennis W; Cravatt, Benjamin F.
Affiliation
  • Backus KM; Department of Chemical Physiology, The Scripps Research Institute. La Jolla, California 92307, USA.
  • Correia BE; Department of Chemical Physiology, The Scripps Research Institute. La Jolla, California 92307, USA.
  • Lum KM; Department of Chemical Physiology, The Scripps Research Institute. La Jolla, California 92307, USA.
  • Forli S; Department of Integrative Structural and Computational Biology, The Scripps Research Institute. La Jolla, California 92307, USA.
  • Horning BD; Department of Chemical Physiology, The Scripps Research Institute. La Jolla, California 92307, USA.
  • González-Páez GE; Department of Molecular and Experimental Medicine, The Scripps Research Institute. La Jolla, California 92307, USA.
  • Chatterjee S; Department of Molecular and Experimental Medicine, The Scripps Research Institute. La Jolla, California 92307, USA.
  • Lanning BR; Department of Chemical Physiology, The Scripps Research Institute. La Jolla, California 92307, USA.
  • Teijaro JR; Department of Immunology and Microbial Science, The Scripps Research Institute. La Jolla, California 92307, USA.
  • Olson AJ; Department of Integrative Structural and Computational Biology, The Scripps Research Institute. La Jolla, California 92307, USA.
  • Wolan DW; Department of Molecular and Experimental Medicine, The Scripps Research Institute. La Jolla, California 92307, USA.
  • Cravatt BF; Department of Chemical Physiology, The Scripps Research Institute. La Jolla, California 92307, USA.
Nature ; 534(7608): 570-4, 2016 06 23.
Article in En | MEDLINE | ID: mdl-27309814
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Proteome / Cysteine / Drug Evaluation, Preclinical / Small Molecule Libraries Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nature Year: 2016 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Proteome / Cysteine / Drug Evaluation, Preclinical / Small Molecule Libraries Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nature Year: 2016 Type: Article Affiliation country: United States