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Hepatic mTORC1 Opposes Impaired Insulin Action to Control Mitochondrial Metabolism in Obesity.
Kucejova, Blanka; Duarte, Joao; Satapati, Santhosh; Fu, Xiaorong; Ilkayeva, Olga; Newgard, Christopher B; Brugarolas, James; Burgess, Shawn C.
Affiliation
  • Kucejova B; AIRC Division of Metabolic Mechanisms of Disease, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Duarte J; AIRC Division of Metabolic Mechanisms of Disease, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Satapati S; AIRC Division of Metabolic Mechanisms of Disease, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Fu X; AIRC Division of Metabolic Mechanisms of Disease, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Ilkayeva O; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Department of Pharmacology and Cancer Biology and Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
  • Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Department of Pharmacology and Cancer Biology and Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
  • Brugarolas J; Kidney Cancer Program, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Burgess SC; AIRC Division of Metabolic Mechanisms of Disease, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: shawn.burgess@utsouthwestern.edu.
Cell Rep ; 16(2): 508-519, 2016 07 12.
Article in En | MEDLINE | ID: mdl-27346353
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitochondria, Liver / Mechanistic Target of Rapamycin Complex 1 / Liver / Obesity Type of study: Etiology_studies Limits: Animals Language: En Journal: Cell Rep Year: 2016 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitochondria, Liver / Mechanistic Target of Rapamycin Complex 1 / Liver / Obesity Type of study: Etiology_studies Limits: Animals Language: En Journal: Cell Rep Year: 2016 Type: Article Affiliation country: United States