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Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine.
Briggs, Kimberly J; Koivunen, Peppi; Cao, Shugeng; Backus, Keriann M; Olenchock, Benjamin A; Patel, Hetalben; Zhang, Qing; Signoretti, Sabina; Gerfen, Gary J; Richardson, Andrea L; Witkiewicz, Agnieszka K; Cravatt, Benjamin F; Clardy, Jon; Kaelin, William G.
Affiliation
  • Briggs KJ; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA 02215, USA.
  • Koivunen P; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, FIN-90014 Oulu, Finland.
  • Cao S; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Backus KM; The Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Olenchock BA; Division of Cardiovascular Medicine, Department of Medicine, The Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Patel H; Department of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Zhang Q; Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Signoretti S; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Gerfen GJ; Department of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Richardson AL; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Witkiewicz AK; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75235, USA.
  • Cravatt BF; The Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Clardy J; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Kaelin WG; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA 02215, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address: william_kaelin@dfci.harvard.edu.
Cell ; 166(1): 126-39, 2016 Jun 30.
Article in En | MEDLINE | ID: mdl-27368101
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Paracrine Communication / Cysteine / Hypoxia-Inducible Factor 1, alpha Subunit / Triple Negative Breast Neoplasms / Hypoxia-Inducible Factor-Proline Dioxygenases Limits: Animals / Humans Language: En Journal: Cell Year: 2016 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Paracrine Communication / Cysteine / Hypoxia-Inducible Factor 1, alpha Subunit / Triple Negative Breast Neoplasms / Hypoxia-Inducible Factor-Proline Dioxygenases Limits: Animals / Humans Language: En Journal: Cell Year: 2016 Type: Article Affiliation country: United States