Antagonizing Self-Renewal in Acute Myeloid Leukemia: ID2 Takes the Stage.
Cancer Cell
; 30(1): 5-7, 2016 07 11.
Article
in En
| MEDLINE
| ID: mdl-27411580
ABSTRACT
E proteins and their functional antagonists, the ID proteins, have significant roles in normal hematopoiesis. In this issue of Cancer Cell, Ghisi et al. show that high ID2 levels antagonize self-renewal and promote differentiation of leukemic stem cells in the MLL-translocated molecular subtype of acute myeloid leukemia.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Leukemia, Myeloid, Acute
/
Cell Differentiation
Limits:
Humans
Language:
En
Journal:
Cancer Cell
Journal subject:
NEOPLASIAS
Year:
2016
Type:
Article
Affiliation country:
United kingdom