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A phase I trial of the human double minute 2 inhibitor (MK-8242) in patients with refractory/recurrent acute myelogenous leukemia (AML).
Ravandi, Farhad; Gojo, Ivana; Patnaik, Mrinal M; Minden, Mark D; Kantarjian, Hagop; Johnson-Levonas, Amy O; Fancourt, Craig; Lam, Raymond; Jones, Mary Beth; Knox, Clayton D; Rose, Shelonitda; Patel, Payal Shah; Tibes, Raoul.
Affiliation
  • Ravandi F; The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address: fravandi@mdanderson.org.
  • Gojo I; Johns Hopkins University, Baltimore, MD, United States.
  • Patnaik MM; Mayo Clinic, Rochester, MN, United States.
  • Minden MD; Princess Margaret Hospital, Toronto, ON, Canada.
  • Kantarjian H; The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
  • Johnson-Levonas AO; Merck & Co., Inc., Kenilworth, NJ, United States.
  • Fancourt C; Merck & Co., Inc., Kenilworth, NJ, United States.
  • Lam R; Merck & Co., Inc., Kenilworth, NJ, United States.
  • Jones MB; Merck & Co., Inc., Kenilworth, NJ, United States.
  • Knox CD; Merck & Co., Inc., Kenilworth, NJ, United States.
  • Rose S; Merck & Co., Inc., Kenilworth, NJ, United States.
  • Patel PS; Merck & Co., Inc., Kenilworth, NJ, United States.
  • Tibes R; MAYO Clinic Arizona, Scottsdale, AZ, United States.
Leuk Res ; 48: 92-100, 2016 09.
Article in En | MEDLINE | ID: mdl-27544076
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Cytarabine / Proto-Oncogene Proteins c-mdm2 Type of study: Clinical_trials Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Leuk Res Year: 2016 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Cytarabine / Proto-Oncogene Proteins c-mdm2 Type of study: Clinical_trials Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Leuk Res Year: 2016 Type: Article