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Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis.
Moran, Sebastian; Martínez-Cardús, Anna; Sayols, Sergi; Musulén, Eva; Balañá, Carme; Estival-Gonzalez, Anna; Moutinho, Cátia; Heyn, Holger; Diaz-Lagares, Angel; de Moura, Manuel Castro; Stella, Giulia M; Comoglio, Paolo M; Ruiz-Miró, Maria; Matias-Guiu, Xavier; Pazo-Cid, Roberto; Antón, Antonio; Lopez-Lopez, Rafael; Soler, Gemma; Longo, Federico; Guerra, Isabel; Fernandez, Sara; Assenov, Yassen; Plass, Christoph; Morales, Rafael; Carles, Joan; Bowtell, David; Mileshkin, Linda; Sia, Daniela; Tothill, Richard; Tabernero, Josep; Llovet, Josep M; Esteller, Manel.
Affiliation
  • Moran S; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet, Barcelona, Catalonia, Spain.
  • Martínez-Cardús A; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet, Barcelona, Catalonia, Spain.
  • Sayols S; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet, Barcelona, Catalonia, Spain.
  • Musulén E; Department of Pathology, Hospital Universitari Germans Trias i Pujol, C/ Ctra de Canyet s/n, Badalona, Barcelona, Catalonia, Spain.
  • Balañá C; Medical Oncology, Catalan Institute of Oncology (ICO), University Hospital Germans Trias i Pujol, Badalona, Barcelona, Catalonia, Spain.
  • Estival-Gonzalez A; Medical Oncology, Catalan Institute of Oncology (ICO), University Hospital Germans Trias i Pujol, Badalona, Barcelona, Catalonia, Spain.
  • Moutinho C; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet, Barcelona, Catalonia, Spain.
  • Heyn H; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet, Barcelona, Catalonia, Spain.
  • Diaz-Lagares A; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet, Barcelona, Catalonia, Spain.
  • de Moura MC; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet, Barcelona, Catalonia, Spain.
  • Stella GM; Cardiothoracic and Vascular Department, Pneumology Unit, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
  • Comoglio PM; Institute for Cancer Research at Candiolo, Candiolo, Italy.
  • Ruiz-Miró M; IRBLleida Biobank, Lleida, Catalonia, Spain.
  • Matias-Guiu X; Department of Pathology and Molecular Genetics/Oncologic Pathology Group, Hospital Universitari Arnau de Vilanova, Universitat de Lleida, IRBLleida, Lleida, Catalonia, Spain.
  • Pazo-Cid R; Medical Oncology Service, Hospital Miguel Servet, Zaragoza, Spain.
  • Antón A; Medical Oncology Service, Hospital Miguel Servet, Zaragoza, Spain.
  • Lopez-Lopez R; Medical Oncology Service, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.
  • Soler G; Medical Oncology, Catalan Institute of Oncology (ICO), Hospital Duran i Reynals, L'Hospitalet de Llobregat, Barcelona, Catalonia, Spain.
  • Longo F; Medical Oncology Service, Hospital Universitario Ramon y Cajal, Madrid, Spain.
  • Guerra I; Biobanco Vasco, Hospital Universitario de Araba, Vitoria, Spain.
  • Fernandez S; Biobanco Vasco, Hospital Universitario de Basurto, Bilbao, Spain.
  • Assenov Y; Division of Epigenomics and Cancer Risk Factors at the German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Plass C; Division of Epigenomics and Cancer Risk Factors at the German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Morales R; Oncology Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona (UAB), Barcelona, Catalonia, Spain; Oncology Department, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Catalonia, Spain.
  • Carles J; Oncology Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona (UAB), Barcelona, Catalonia, Spain; Oncology Department, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Catalonia, Spain.
  • Bowtell D; The Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia; The Department of Pathology, University of Melbourne, Parkville, VIC, Australia.
  • Mileshkin L; The Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia; The Department of Pathology, University of Melbourne, Parkville, VIC, Australia.
  • Sia D; Liver Cancer Program, Division of Liver Diseases, Tisch Cancer Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Tothill R; The Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; The Department of Pathology, University of Melbourne, Parkville, VIC, Australia.
  • Tabernero J; Oncology Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona (UAB), Barcelona, Catalonia, Spain; Oncology Department, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Catalonia, Spain.
  • Llovet JM; Liver Cancer Translational Research Laboratory, Barcelona Clinic Liver Cancer (BCLC) Group, Liver Unit, IDIBAPS, Hospital Clínic, CIBERehd, Barcelona, Catalonia, Spain; School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain; Institucio Catalana de Recerca i Estudis Avançats (ICREA)
  • Esteller M; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet, Barcelona, Catalonia, Spain; School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain; Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spai
Lancet Oncol ; 17(10): 1386-1395, 2016 Oct.
Article in En | MEDLINE | ID: mdl-27575023
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplasms, Unknown Primary / DNA Methylation / Epigenesis, Genetic Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Lancet Oncol Journal subject: NEOPLASIAS Year: 2016 Type: Article Affiliation country: Spain
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplasms, Unknown Primary / DNA Methylation / Epigenesis, Genetic Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Lancet Oncol Journal subject: NEOPLASIAS Year: 2016 Type: Article Affiliation country: Spain