Evaluation of antibacterial and antibiofilm mechanisms by usnic acid against methicillin-resistant Staphylococcus aureus.

Pompilio, Arianna; Riviello, Antonella; Crocetta, Valentina; Di Giuseppe, Fabrizio; Pomponio, Stefano; Sulpizio, Marilisa; Di Ilio, Carmine; Angelucci, Stefania; Barone, Luana; Di Giulio, Andrea; Di Bonaventura, Giovanni

Pompilio, Arianna; Riviello, Antonella; Crocetta, Valentina; Di Giuseppe, Fabrizio; Pomponio, Stefano; Sulpizio, Marilisa; Di Ilio, Carmine; Angelucci, Stefania; Barone, Luana; Di Giulio, Andrea; Di Bonaventura, Giovanni.

Affiliation

Pompilio A; Department of Medical, Oral & Biotechnological Sciences, 'G d'Annunzio' University of Chieti-Pescara, Via Vestini 31, Chieti, Italy.
Riviello A; Aging Research Center and Translational Medicine, 'G d'Annunzio' University of Chieti-Pescara, Via L Polacchi 13, Chieti, Italy.
Crocetta V; Department of Medical, Oral & Biotechnological Sciences, 'G d'Annunzio' University of Chieti-Pescara, Via Vestini 31, Chieti, Italy.
Di Giuseppe F; Aging Research Center and Translational Medicine, 'G d'Annunzio' University of Chieti-Pescara, Via L Polacchi 13, Chieti, Italy.
Pomponio S; Stem TeCh Group, Via L Polacchi 13, Chieti, Italy.
Sulpizio M; Department of Medical, Oral & Biotechnological Sciences, 'G d'Annunzio' University of Chieti-Pescara, Via Vestini 31, Chieti, Italy.
Di Ilio C; Aging Research Center and Translational Medicine, 'G d'Annunzio' University of Chieti-Pescara, Via L Polacchi 13, Chieti, Italy.
Angelucci S; Department of Medical, Oral & Biotechnological Sciences, 'G d'Annunzio' University of Chieti-Pescara, Via Vestini 31, Chieti, Italy.
Barone L; Aging Research Center and Translational Medicine, 'G d'Annunzio' University of Chieti-Pescara, Via L Polacchi 13, Chieti, Italy.
Di Giulio A; Stem TeCh Group, Via L Polacchi 13, Chieti, Italy.
Di Bonaventura G; Department of Medical, Oral & Biotechnological Sciences, 'G d'Annunzio' University of Chieti-Pescara, Via Vestini 31, Chieti, Italy.

Future Microbiol ; 11: 1315-1338, 2016 10.

Article in En | MEDLINE | ID: mdl-27633726

Subject(s)

Anti-Bacterial Agents/pharmacology; Benzofurans/pharmacology; Biofilms/drug effects; Methicillin-Resistant Staphylococcus aureus/drug effects; Adhesins, Bacterial/drug effects; Anti-Bacterial Agents/administration & dosage; Bacterial Proteins/antagonists & inhibitors; Bacterial Proteins/drug effects; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Benzofurans/administration & dosage; Carrier Proteins/drug effects; Cell Membrane/drug effects; Cell Survival/drug effects; Colony Count, Microbial; Cystic Fibrosis/drug therapy; Cystic Fibrosis/microbiology; DNA, Bacterial; Down-Regulation; Lipase/drug effects; Methicillin-Resistant Staphylococcus aureus/genetics; Methicillin-Resistant Staphylococcus aureus/pathogenicity; Methicillin-Resistant Staphylococcus aureus/ultrastructure; Microbial Sensitivity Tests; Microbial Viability/drug effects; Microscopy, Electron, Scanning/methods; Microscopy, Electron, Transmission/methods; Peptidoglycan/biosynthesis; Peptidoglycan/drug effects; Propidium/metabolism; Protein Interaction Maps; Proteomics/methods; Real-Time Polymerase Chain Reaction/methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods; Staphylococcal Infections/microbiology; Time Factors; Virulence/drug effects; Virulence/genetics

Key words

Staphylococcus aureus; biofilm; usnic acid

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Collection: 01-internacional Database: MEDLINE Main subject: Benzofurans / Biofilms / Methicillin-Resistant Staphylococcus aureus / Anti-Bacterial Agents Language: En Journal: Future Microbiol Journal subject: MICROBIOLOGIA Year: 2016 Type: Article Affiliation country: Italy

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