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Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.
Singh, Vinayak; Dhar, Neeraj; Pató, János; Kolly, Gaëlle S; Korduláková, Jana; Forbak, Martin; Evans, Joanna C; Székely, Rita; Rybniker, Jan; Palceková, Zuzana; Zemanová, Júlia; Santi, Isabella; Signorino-Gelo, François; Rodrigues, Liliana; Vocat, Anthony; Covarrubias, Adrian S; Rengifo, Monica G; Johnsson, Kai; Mowbray, Sherry; Buechler, Joseph; Delorme, Vincent; Brodin, Priscille; Knott, Graham W; Aínsa, José A; Warner, Digby F; Kéri, György; Mikusová, Katarína; McKinney, John D; Cole, Stewart T; Mizrahi, Valerie; Hartkoorn, Ruben C.
Affiliation
  • Singh V; Institute of Infectious Disease and Molecular Medicine & Department of Pathology, University of Cape Town, MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research, South Africa.
  • Dhar N; Microbiology and Microsystems, Global Health Institute, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland.
  • Pató J; Vichem Chemie Research Ltd, Herman, Otto u. 15, Budapest, 1022, Hungary.
  • Kolly GS; Microbial Pathogenesis, Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Korduláková J; Now at: 1st Department of Internal Medicine, University of Cologne, Cologne, Germany.
  • Forbak M; Now at: 1st Department of Internal Medicine, University of Cologne, Cologne, Germany.
  • Evans JC; Institute of Infectious Disease and Molecular Medicine & Department of Pathology, University of Cape Town, MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research, South Africa.
  • Székely R; Microbial Pathogenesis, Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Rybniker J; Microbial Pathogenesis, Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Palceková Z; Now at: 1st Department of Internal Medicine, University of Cologne, Cologne, Germany.
  • Zemanová J; Faculty of Natural Sciences, Department of Biochemistry, Comenius University in Bratislava, Bratislava, Slovakia.
  • Santi I; Faculty of Natural Sciences, Department of Biochemistry, Comenius University in Bratislava, Bratislava, Slovakia.
  • Signorino-Gelo F; Microbiology and Microsystems, Global Health Institute, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland.
  • Rodrigues L; Microbiology and Microsystems, Global Health Institute, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland.
  • Vocat A; Departamento de Microbiología, Facultad de Medicina, Universidad de Zaragoza, and Fundación ARAID, Zaragoza, Spain; CIBERES, Instituto de Salud Carlos III, Madrid, Zaragoza, Spain.
  • Covarrubias AS; Microbial Pathogenesis, Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Rengifo MG; Department of Cell and Molecular Biology, Uppsala University, Biomedical Center, Uppsala, Sweden.
  • Johnsson K; Institute of Chemical Sciences and Engineering (ISIC), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Mowbray S; Institute of Chemical Sciences and Engineering (ISIC), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Buechler J; Department of Cell and Molecular Biology, Uppsala University, Biomedical Center, Uppsala, Sweden.
  • Delorme V; Alere (San Diego), Summer Ridge Road, San Diego, CA, 92121, USA.
  • Brodin P; Center for Infection and Immunity, Inserm U1019, CNRS UMR8204, Institut Pasteur de Lille, Université de Lille, Lille, France.
  • Knott GW; Center for Infection and Immunity, Inserm U1019, CNRS UMR8204, Institut Pasteur de Lille, Université de Lille, Lille, France.
  • Aínsa JA; Interdisciplinary Centre for Electron Microscopy, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Warner DF; Departamento de Microbiología, Facultad de Medicina, Universidad de Zaragoza, and Fundación ARAID, Zaragoza, Spain; CIBERES, Instituto de Salud Carlos III, Madrid, Zaragoza, Spain.
  • Kéri G; Institute of Infectious Disease and Molecular Medicine & Department of Pathology, University of Cape Town, MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research, South Africa.
  • Mikusová K; Vichem Chemie Research Ltd, Herman, Otto u. 15, Budapest, 1022, Hungary.
  • McKinney JD; Faculty of Natural Sciences, Department of Biochemistry, Comenius University in Bratislava, Bratislava, Slovakia.
  • Cole ST; Microbiology and Microsystems, Global Health Institute, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland.
  • Mizrahi V; Microbial Pathogenesis, Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Hartkoorn RC; Institute of Infectious Disease and Molecular Medicine & Department of Pathology, University of Cape Town, MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research, South Africa.
Mol Microbiol ; 103(1): 13-25, 2017 01.
Article in En | MEDLINE | ID: mdl-27677649

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Bacterial Proteins / Antitubercular Agents Type of study: Diagnostic_studies Language: En Journal: Mol Microbiol Journal subject: BIOLOGIA MOLECULAR / MICROBIOLOGIA Year: 2017 Type: Article Affiliation country: South Africa

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Bacterial Proteins / Antitubercular Agents Type of study: Diagnostic_studies Language: En Journal: Mol Microbiol Journal subject: BIOLOGIA MOLECULAR / MICROBIOLOGIA Year: 2017 Type: Article Affiliation country: South Africa