Extremely low frequency pulsed electromagnetic fields increase interleukin-2 (IL-2) utilization and IL-2 receptor expression in mitogen-stimulated human lymphocytes from old subjects.
FEBS Lett
; 248(1-2): 141-4, 1989 May 08.
Article
in En
| MEDLINE
| ID: mdl-2785933
ABSTRACT
The effects of the exposure of mitogen-stimulated human lymphocytes from aged subjects to low-frequency pulsed electromagnetic fields (PEMFs) were studied by measuring the production of interleukin-2 (IL-2) and the expression of IL-2 receptor. PEMF-exposed cultures that presented increased [3H]thymidine incorporation showed lower amounts of IL-2 in their supernatants, but higher percentages of IL-2 receptor-positive cells and of T-activated lymphocytes. Taken together, these data suggest that PEMFs were able to modulate mitogen-induced lymphocyte proliferation by provoking an increase in utilization of IL-2, most likely acting on the expression of its receptor on the plasma membrane.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Aged, 80 and over
/
Lymphocytes
/
Receptors, Interleukin-2
/
Interleukin-2
/
Electromagnetic Fields
/
Electromagnetic Phenomena
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
En
Journal:
FEBS Lett
Year:
1989
Type:
Article
Affiliation country:
Italy