Trophoblast cells inhibit neutrophil extracellular trap formation and enhance apoptosis through vasoactive intestinal peptide-mediated pathways.

Calo, Guillermina; Sabbione, Florencia; Vota, Daiana; Paparini, Daniel; Ramhorst, Rosanna; Trevani, Analía; Pérez Leirós, Claudia

Calo, Guillermina; Sabbione, Florencia; Vota, Daiana; Paparini, Daniel; Ramhorst, Rosanna; Trevani, Analía; Pérez Leirós, Claudia.

Affiliation

Calo G; CONICET, Facultad de Ciencias Exactas y Naturales, Instituto de Química Biológica (IQUIBICEN), Universidad de Buenos Aires, Ciudad Universitaria, Pab II. Fourth Floor, 1428 Buenos Aires, Argentina.
Sabbione F; CONICET, Facultad de Medicina, Instituto de Medicina Experimental, Academia Nacional de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Vota D; CONICET, Facultad de Ciencias Exactas y Naturales, Instituto de Química Biológica (IQUIBICEN), Universidad de Buenos Aires, Ciudad Universitaria, Pab II. Fourth Floor, 1428 Buenos Aires, Argentina.
Paparini D; CONICET, Facultad de Ciencias Exactas y Naturales, Instituto de Química Biológica (IQUIBICEN), Universidad de Buenos Aires, Ciudad Universitaria, Pab II. Fourth Floor, 1428 Buenos Aires, Argentina.
Ramhorst R; CONICET, Facultad de Ciencias Exactas y Naturales, Instituto de Química Biológica (IQUIBICEN), Universidad de Buenos Aires, Ciudad Universitaria, Pab II. Fourth Floor, 1428 Buenos Aires, Argentina.
Trevani A; CONICET, Facultad de Medicina, Instituto de Medicina Experimental, Academia Nacional de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Pérez Leirós C; CONICET, Facultad de Ciencias Exactas y Naturales, Instituto de Química Biológica (IQUIBICEN), Universidad de Buenos Aires, Ciudad Universitaria, Pab II. Fourth Floor, 1428 Buenos Aires, Argentina cpleiros@qb.fcen.uba.ar.

Hum Reprod ; 32(1): 55-64, 2017 01.

Article in En | MEDLINE | ID: mdl-27932441

Subject(s)

Apoptosis/physiology; Extracellular Traps/metabolism; Signal Transduction/physiology; Trophoblasts/metabolism; Vasoactive Intestinal Peptide/pharmacology; Apoptosis/drug effects; Cell Line; Culture Media, Conditioned/pharmacology; Extracellular Traps/drug effects; Female; Humans; Neutrophils/drug effects; Neutrophils/metabolism; Phagocytosis/drug effects; Phagocytosis/physiology; Pregnancy; Reactive Oxygen Species/metabolism; Signal Transduction/drug effects; Trophoblasts/drug effects

Key words

neutrophil apoptosis; neutrophil extracellular traps; neutrophils; phagocytosis of apoptotic cells; trophoblast cells; vasoactive intestinal peptide

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Trophoblasts / Vasoactive Intestinal Peptide / Signal Transduction / Apoptosis / Extracellular Traps Type of study: Observational_studies / Prognostic_studies Limits: Female / Humans / Pregnancy Language: En Journal: Hum Reprod Journal subject: MEDICINA REPRODUTIVA Year: 2017 Type: Article Affiliation country: Argentina

Search on Google

XML

PubMed Links