Lithium Dihydropyridine Dehydrogenation Catalysis: A Groupâ
1 Approach to the Cyclization of Diamine Boranes.
Angew Chem Int Ed Engl
; 56(4): 1036-1041, 2017 01 19.
Article
in En
| MEDLINE
| ID: mdl-28000994
ABSTRACT
In reactions restricted previously to a ruthenium catalyst, a 1-lithium-2-alkyl-1,2-dihydropyridine complex is shown to be a competitive alternative dehydrogenation catalyst for the transformation of diamine boranes into cyclic 1,3,2-diazaborolidines, which can in turn be smoothly arylated in good yields. This study established the conditions and solvent dependence of the catalysis through NMR monitoring, with mechanistic insight provided by NMR (including DOSY) experiments and X-ray crystallographic studies of several model lithio intermediates.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Angew Chem Int Ed Engl
Year:
2017
Type:
Article
Affiliation country:
United kingdom