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Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors.
Torok, Szilvia; Rezeli, Melinda; Kelemen, Olga; Vegvari, Akos; Watanabe, Kenichi; Sugihara, Yutaka; Tisza, Anna; Marton, Timea; Kovacs, Ildiko; Tovari, Jozsef; Laszlo, Viktoria; Helbich, Thomas H; Hegedus, Balazs; Klikovits, Thomas; Hoda, Mir Alireza; Klepetko, Walter; Paku, Sandor; Marko-Varga, Gyorgy; Dome, Balazs.
Affiliation
  • Torok S; National Korányi Institute of Pulmonology, Budapest, Hungary;; Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria;; Clinical Protein Science&Imaging, Biomedical Center, Dept. of Biomedical Engineering, Lund University, Sweden;;
  • Rezeli M; Clinical Protein Science&Imaging, Biomedical Center, Dept. of Biomedical Engineering, Lund University, Sweden.
  • Kelemen O; National Korányi Institute of Pulmonology, Budapest, Hungary;; Clinical Protein Science&Imaging, Biomedical Center, Dept. of Biomedical Engineering, Lund University, Sweden.
  • Vegvari A; Clinical Protein Science&Imaging, Biomedical Center, Dept. of Biomedical Engineering, Lund University, Sweden;; Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX, USA.
  • Watanabe K; Clinical Protein Science&Imaging, Biomedical Center, Dept. of Biomedical Engineering, Lund University, Sweden.
  • Sugihara Y; Clinical Protein Science&Imaging, Biomedical Center, Dept. of Biomedical Engineering, Lund University, Sweden;; Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Sweden.
  • Tisza A; National Korányi Institute of Pulmonology, Budapest, Hungary.
  • Marton T; National Korányi Institute of Pulmonology, Budapest, Hungary.
  • Kovacs I; National Korányi Institute of Pulmonology, Budapest, Hungary.
  • Tovari J; Department of Experimental Pharmacology, National Institute of Oncology, Budapest, Hungary.
  • Laszlo V; Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria;; Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria.
  • Helbich TH; Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria.
  • Hegedus B; Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria;; Department of Thoracic Surgery, Ruhrlandklinik, University Clinic Essen, Germany;; Hungarian Academy of Sciences-Semmelweis University, Tumor Progression Research Group, Budapest
  • Klikovits T; Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria.
  • Hoda MA; Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria.
  • Klepetko W; Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria.
  • Paku S; Hungarian Academy of Sciences-Semmelweis University, Tumor Progression Research Group, Budapest, Hungary;; 1st Institute of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary.
  • Marko-Varga G; Clinical Protein Science&Imaging, Biomedical Center, Dept. of Biomedical Engineering, Lund University, Sweden;; Center of Excellence in Biological and Medical Mass Spectrometry, Lund University, Sweden.
  • Dome B; National Korányi Institute of Pulmonology, Budapest, Hungary;; Division of Thoracic Surgery, Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Austria;; Department of Thoracic Surgery, Semmelweis University and National Institute of Oncology, Budapest, Hungary;; Depar
Theranostics ; 7(2): 400-412, 2017.
Article in En | MEDLINE | ID: mdl-28042343
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Resistance / Angiogenesis Inhibitors / Enzyme Inhibitors / Neoplasms Type of study: Prognostic_studies Limits: Animals Language: En Journal: Theranostics Year: 2017 Type: Article
Fulltext
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Resistance / Angiogenesis Inhibitors / Enzyme Inhibitors / Neoplasms Type of study: Prognostic_studies Limits: Animals Language: En Journal: Theranostics Year: 2017 Type: Article