Your browser doesn't support javascript.
loading
Sudden benzodiazepine-induced resolution of post-operative pediatric cerebellar mutism syndrome: a clinical-SPECT study.
Nicita, Francesco; Paiano, Milena; Liberatore, Mauro; Spalice, Alberto; Papoff, Paola; Ullo, Mariacristina; Piccirilli, Manolo; Clerico, Anna; Schiavetti, Amalia.
Affiliation
  • Nicita F; Child Neurology Division, Department of Pediatrics and Child Neuropsychiatry, Umberto I Hospital, Sapienza University of Rome, Viale Regina Elena 324, 00161, Roma, Italy. nicita.f@gmail.com.
  • Paiano M; Pediatric Oncology Division, Department of Pediatrics and Child Neuropsychiatry, Umberto I Hospital, Sapienza University of Rome, Rome, Italy.
  • Liberatore M; Section of Nuclear Medicine, Department of Radiological, Oncological and Anatomo-Pathological Sciences, Umberto I Hospital, Sapienza University of Rome, Rome, Italy.
  • Spalice A; Child Neurology Division, Department of Pediatrics and Child Neuropsychiatry, Umberto I Hospital, Sapienza University of Rome, Viale Regina Elena 324, 00161, Roma, Italy.
  • Papoff P; Pediatric Intensive Care Unit, Department of Pediatrics and Child Neuropsychiatry, Umberto I Hospital, Sapienza University of Rome, Rome, Italy.
  • Ullo M; Section of Nuclear Medicine, Department of Radiological, Oncological and Anatomo-Pathological Sciences, Umberto I Hospital, Sapienza University of Rome, Rome, Italy.
  • Piccirilli M; Department of Neurosurgery, Umberto I Hospital, Sapienza University of Rome, Rome, Italy.
  • Clerico A; Pediatric Oncology Division, Department of Pediatrics and Child Neuropsychiatry, Umberto I Hospital, Sapienza University of Rome, Rome, Italy.
  • Schiavetti A; Pediatric Oncology Division, Department of Pediatrics and Child Neuropsychiatry, Umberto I Hospital, Sapienza University of Rome, Rome, Italy.
Acta Neurochir (Wien) ; 159(3): 475-479, 2017 03.
Article in En | MEDLINE | ID: mdl-28050719
ABSTRACT
Post-operative pediatric cerebellar mutism syndrome (PPCMS) is a clinical syndrome arising from cerebellar injury and characterized by absence of speech and other possible symptoms and signs. Rare reports described some benefit after administration of dopamine agonist therapy, but no treatment has proven efficacy. In this paper, we report on the dramatic, sudden resolution of PPCMS induced by midazolam administration in a boy who underwent posterior fossa surgery for choroid plexus papilloma of the fourth ventricle. In addition to clinical improvement, post-midazolam single-photon emission computed tomography also demonstrated amelioration of brain perfusion.
Subject(s)
Key words
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Papilloma / Postoperative Complications / Benzodiazepines / Midazolam / Cerebellar Diseases / Cerebral Ventricle Neoplasms / Hypnotics and Sedatives / Mutism Type of study: Etiology_studies Limits: Adolescent / Humans / Male Language: En Journal: Acta Neurochir (Wien) Year: 2017 Type: Article Affiliation country: Italy
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Papilloma / Postoperative Complications / Benzodiazepines / Midazolam / Cerebellar Diseases / Cerebral Ventricle Neoplasms / Hypnotics and Sedatives / Mutism Type of study: Etiology_studies Limits: Adolescent / Humans / Male Language: En Journal: Acta Neurochir (Wien) Year: 2017 Type: Article Affiliation country: Italy