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Antibodies Targeting Closely Adjacent or Minimally Overlapping Epitopes Can Displace One Another.
Abdiche, Yasmina Noubia; Yeung, Andy Yik; Ni, Irene; Stone, Donna; Miles, Adam; Morishige, Winse; Rossi, Andrea; Strop, Pavel.
Affiliation
  • Abdiche YN; Department of Protein Engineering, Rinat, Oncology Research and Development, Pfizer Inc., South San Francisco, California, United States of America.
  • Yeung AY; Department of Protein Engineering, Rinat, Oncology Research and Development, Pfizer Inc., South San Francisco, California, United States of America.
  • Ni I; Department of Protein Engineering, Rinat, Oncology Research and Development, Pfizer Inc., South San Francisco, California, United States of America.
  • Stone D; Department of Protein Engineering, Rinat, Oncology Research and Development, Pfizer Inc., South San Francisco, California, United States of America.
  • Miles A; Wasatch Microfluidics, Salt Lake City, Utah, United States of America.
  • Morishige W; Department of Protein Engineering, Bristol-Myers Squibb, Redwood City, California, United States of America.
  • Rossi A; Compugen USA Inc., South San Francisco, California, United States of America.
  • Strop P; Department of Protein Engineering, Bristol-Myers Squibb, Redwood City, California, United States of America.
PLoS One ; 12(1): e0169535, 2017.
Article in En | MEDLINE | ID: mdl-28060885
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biosensing Techniques / Epitope Mapping / Antibodies, Monoclonal / Epitopes Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2017 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biosensing Techniques / Epitope Mapping / Antibodies, Monoclonal / Epitopes Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2017 Type: Article Affiliation country: United States