Eyedrop Inoculation Causes Sublethal Leptospirosis in Mice.

Sullivan, Joseph Pierce; Nair, Nisha; Potula, Hari-Hara; Gomes-Solecki, Maria

Sullivan, Joseph Pierce; Nair, Nisha; Potula, Hari-Hara; Gomes-Solecki, Maria.

Affiliation

Sullivan JP; Department of Comparative Medicine, University of Tennessee Health Science Center, College of Medicine, Memphis, Tennessee, USA.
Nair N; Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Potula HH; Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Gomes-Solecki M; Immuno Technologies Inc., Memphis, Tennessee, USA.

Infect Immun ; 85(4)2017 04.

Article in En | MEDLINE | ID: mdl-28115508

Subject(s)

Leptospira interrogans; Leptospirosis/microbiology; Leptospirosis/transmission; Ophthalmic Solutions; Animals; Antibodies, Bacterial/immunology; Chemotaxis, Leukocyte/immunology; Conjunctivitis, Bacterial/immunology; Conjunctivitis, Bacterial/microbiology; Conjunctivitis, Bacterial/pathology; Conjunctivitis, Bacterial/transmission; Cytokines/metabolism; Disease Models, Animal; Immunoglobulin G/immunology; Immunoglobulin M/immunology; Inflammation Mediators/metabolism; Leptospira interrogans/immunology; Leptospirosis/immunology; Leptospirosis/mortality; Mice; Mice, Inbred C3H; Nephritis/immunology; Nephritis/microbiology; Nephritis/pathology; Ophthalmic Solutions/adverse effects

Key words

C3H/HeJ; Leptospira; conjunctiva; enzootic transmission; inflammation; mouse model; sublethal infection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ophthalmic Solutions / Leptospira interrogans / Leptospirosis Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Infect Immun Year: 2017 Type: Article Affiliation country: United States

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