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Targeting the HDAC2/HNF-4A/miR-101b/AMPK Pathway Rescues Tauopathy and Dendritic Abnormalities in Alzheimer's Disease.
Liu, Dan; Tang, Hui; Li, Xin-Yan; Deng, Man-Fei; Wei, Na; Wang, Xiong; Zhou, Ya-Fan; Wang, Ding-Qi; Fu, Peng; Wang, Jian-Zhi; Hébert, Sébastien S; Chen, Jian-Guo; Lu, Youming; Zhu, Ling-Qiang.
Affiliation
  • Liu D; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan 430030, China; Department of Medical Genetics, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Chin
  • Tang H; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan 430030, China; Department of Pathophysiology, Key Laboratory of Ministry of Education for Neurological Disorders, School of Basic Medicine, Tongji Medical College
  • Li XY; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Deng MF; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Wei N; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Wang X; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Zhou YF; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Wang DQ; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Fu P; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
  • Wang JZ; Department of Pathophysiology, Key Laboratory of Ministry of Education for Neurological Disorders, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Hébert SS; Axe Neurosciences, Centre de recherche du CHU de Québec, CHUL, Québec, QC G1V 4G2, Canada; Département de psychiatrie et neurosciences, Université Laval, Québec, QC G1V 0A6, Canada.
  • Chen JG; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan 430030, China; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Lu Y; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Zhu LQ; The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan 430030, China; Department of Pathophysiology, Key Laboratory of Ministry of Education for Neurological Disorders, School of Basic Medicine, Tongji Medical College
Mol Ther ; 25(3): 752-764, 2017 03 01.
Article in En | MEDLINE | ID: mdl-28202389

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tauopathies / MicroRNAs / Hepatocyte Nuclear Factor 4 / AMP-Activated Protein Kinases / Histone Deacetylase 2 / Alzheimer Disease Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2017 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tauopathies / MicroRNAs / Hepatocyte Nuclear Factor 4 / AMP-Activated Protein Kinases / Histone Deacetylase 2 / Alzheimer Disease Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2017 Type: Article