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Metoprolol-pridopidine drug-drug interaction and food effect assessments of pridopidine, a new drug for treatment of Huntington's disease.
Rabinovich-Guilatt, Laura; Steiner, Lilach; Hallak, Hussein; Pastino, Gina; Muglia, Pierandrea; Spiegelstein, Ofer.
Affiliation
  • Rabinovich-Guilatt L; Clinical Pharmacology & Pharmacometrics, Teva Pharmaceutical Industries Ltd, Malvern PA, USA.
  • Steiner L; Drug Metabolism and Pharmacokinetics, Teva Pharmaceutical Industries Ltd, Netanya, Israel.
  • Hallak H; Drug Metabolism and Pharmacokinetics, Teva Pharmaceutical Industries Ltd, Netanya, Israel.
  • Pastino G; Clinical Pharmacology & Pharmacometrics, Teva Pharmaceutical Industries Ltd, Malvern PA, USA.
  • Muglia P; Neuroscience Discovery Medicine UCB Pharma Chemin du Foriest, Belgium.
  • Spiegelstein O; Clinical Pharmacology & Pharmacometrics, Teva Pharmaceutical Industries Ltd, Netanya, Israel.
Br J Clin Pharmacol ; 83(10): 2214-2224, 2017 Oct.
Article in En | MEDLINE | ID: mdl-28449367

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Huntington Disease / Food-Drug Interactions / Cytochrome P-450 CYP2D6 / Cytochrome P-450 CYP2D6 Inhibitors / Metoprolol Type of study: Clinical_trials / Prognostic_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: Br J Clin Pharmacol Year: 2017 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Huntington Disease / Food-Drug Interactions / Cytochrome P-450 CYP2D6 / Cytochrome P-450 CYP2D6 Inhibitors / Metoprolol Type of study: Clinical_trials / Prognostic_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: Br J Clin Pharmacol Year: 2017 Type: Article Affiliation country: United States