Your browser doesn't support javascript.
loading
RNA-seq analyses reveal that cervical spinal cords and anterior motor neurons from amyotrophic lateral sclerosis subjects show reduced expression of mitochondrial DNA-encoded respiratory genes, and rhTFAM may correct this respiratory deficiency.
Ladd, Amy C; Brohawn, David G; Thomas, Ravindar R; Keeney, Paula M; Berr, Stuart S; Khan, Shaharyar M; Portell, Francisco R; Shakenov, Meiram Zh; Antkowiak, Patrick F; Kundu, Bijoy; Tustison, Nicholas; Bennett, James P.
Affiliation
  • Ladd AC; Parkinson's Disease Research Center, Virginia Commonwealth University, Richmond, VA, USA.
  • Brohawn DG; Parkinson's Disease Research Center, Virginia Commonwealth University, Richmond, VA, USA; Department of Human Genetics, Virginia Commonwealth University, Richmond, VA, USA.
  • Thomas RR; Parkinson's Disease Research Center, Virginia Commonwealth University, Richmond, VA, USA.
  • Keeney PM; Parkinson's Disease Research Center, Virginia Commonwealth University, Richmond, VA, USA; Department of Neurology, Virginia Commonwealth University, Richmond, VA, USA; Neurodegeneration Therapeutics, Inc., Charlottesville, VA, USA.
  • Berr SS; Department of Radiology, University of Virginia, Charlottesville, VA, USA.
  • Khan SM; Gencia Corporation, LLC, Charlottesville, VA, USA.
  • Portell FR; Gencia Corporation, LLC, Charlottesville, VA, USA.
  • Shakenov MZ; Department of Science and Education, University Medical Center Corporate Fund, National Center for Children's Rehabilitation, Astana, Kazakhstan.
  • Antkowiak PF; Department of Radiology, University of Virginia, Charlottesville, VA, USA.
  • Kundu B; Department of Radiology, University of Virginia, Charlottesville, VA, USA.
  • Tustison N; Department of Radiology, University of Virginia, Charlottesville, VA, USA.
  • Bennett JP; Parkinson's Disease Research Center, Virginia Commonwealth University, Richmond, VA, USA; Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, VA, USA; Department of Neurology, Virginia Commonwealth University, Richmond, VA, USA; Neurodegeneration Therapeutics, Inc.,
Brain Res ; 1667: 74-83, 2017 07 15.
Article in En | MEDLINE | ID: mdl-28511992
Subject(s)
Key words
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Mitochondrial Proteins / DNA-Binding Proteins / Cervical Cord / Amyotrophic Lateral Sclerosis / Motor Neurons Limits: Animals / Humans / Male Language: En Journal: Brain Res Year: 2017 Type: Article Affiliation country: United States
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Mitochondrial Proteins / DNA-Binding Proteins / Cervical Cord / Amyotrophic Lateral Sclerosis / Motor Neurons Limits: Animals / Humans / Male Language: En Journal: Brain Res Year: 2017 Type: Article Affiliation country: United States