Improvement of isopropanol tolerance of Escherichia coli using adaptive laboratory evolution and omics technologies.

Horinouchi, Takaaki; Sakai, Aki; Kotani, Hazuki; Tanabe, Kumi; Furusawa, Chikara

Horinouchi, Takaaki; Sakai, Aki; Kotani, Hazuki; Tanabe, Kumi; Furusawa, Chikara.

Affiliation

Horinouchi T; Quantitative Biology Center, RIKEN, 6-2-3 Furuedai, Suita, Osaka 565-0874, Japan. Electronic address: takaaki_horinouchi@riken.jp.
Sakai A; Quantitative Biology Center, RIKEN, 6-2-3 Furuedai, Suita, Osaka 565-0874, Japan.
Kotani H; Quantitative Biology Center, RIKEN, 6-2-3 Furuedai, Suita, Osaka 565-0874, Japan.
Tanabe K; Quantitative Biology Center, RIKEN, 6-2-3 Furuedai, Suita, Osaka 565-0874, Japan.
Furusawa C; Quantitative Biology Center, RIKEN, 6-2-3 Furuedai, Suita, Osaka 565-0874, Japan; Universal Biology Institute, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. Electronic address: chikara.furusawa@riken.jp.

J Biotechnol ; 255: 47-56, 2017 Aug 10.

Article in En | MEDLINE | ID: mdl-28645581

Subject(s)

2-Propanol/pharmacology; Escherichia coli Proteins/genetics; Escherichia coli/growth & development; Gene Expression Profiling/methods; Mutation; 2-Propanol/chemistry; Biosynthetic Pathways/drug effects; Directed Molecular Evolution; Drug Resistance, Bacterial; Energy Metabolism/drug effects; Escherichia coli/drug effects; Escherichia coli/genetics; Gene Expression Regulation, Bacterial/drug effects; Ligases/genetics; RNA-Binding Proteins/genetics; Sequence Analysis, RNA/methods

Key words

Adaptive laboratory evolution; Escherichia coli; Genome re-sequence; Isopropanol; Transcriptome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: 2-Propanol / Gene Expression Profiling / Escherichia coli Proteins / Escherichia coli / Mutation Language: En Journal: J Biotechnol Journal subject: BIOTECNOLOGIA Year: 2017 Type: Article

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