Epidermal Growth Factor Receptor activation promotes ADA3 acetylation through the AKT-p300 pathway.

Srivastava, Shashank; Mohibi, Shakur; Mirza, Sameer; Band, Hamid; Band, Vimla

Srivastava, Shashank; Mohibi, Shakur; Mirza, Sameer; Band, Hamid; Band, Vimla.

Affiliation

Srivastava S; a Genetics, Cell Biology and Anatomy , University of Nebraska Medical Center , Omaha , NE , USA.
Mohibi S; a Genetics, Cell Biology and Anatomy , University of Nebraska Medical Center , Omaha , NE , USA.
Mirza S; a Genetics, Cell Biology and Anatomy , University of Nebraska Medical Center , Omaha , NE , USA.
Band H; a Genetics, Cell Biology and Anatomy , University of Nebraska Medical Center , Omaha , NE , USA.
Band V; b Pathology & Microbiology , University of Nebraska Medical Center , Omaha , NE , USA.

Cell Cycle ; 16(16): 1515-1525, 2017 Aug 18.

Article in En | MEDLINE | ID: mdl-28759294

Subject(s)

ErbB Receptors/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Signal Transduction; Transcription Factors/metabolism; p300-CBP Transcription Factors/metabolism; Acetylation; Cell Cycle/drug effects; Cell Line, Tumor; Cell Proliferation/drug effects; Epidermal Growth Factor/pharmacology; Gene Knockdown Techniques; Humans; Lapatinib; Models, Biological; Mutation/genetics; Phosphorylation/drug effects; Protein Stability/drug effects; Quinazolines/pharmacology; Receptor, ErbB-2/metabolism; Signal Transduction/drug effects; Ubiquitination/drug effects

Key words

ADA3; AKT; HAT complex; HER2; SAGA complex; acetylation; lapatinib; p300; phosphorylation; ubiquitination

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Signal Transduction / P300-CBP Transcription Factors / Proto-Oncogene Proteins c-akt / ErbB Receptors Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cell Cycle Year: 2017 Type: Article Affiliation country: United States

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